Bacillus Clausii Spore Suspension Uses, Benefits, Side Effects and Precautions

Bacillus Clausii Spores Suspension Uses, Side Effects, Doses, Benefits and Precautions

Bacillus Clausii spores suspension belongs to the group of drugs called probiotics, that are used to treat unbalanced intestinal bacterial flora. An imbalanced intestinal flora condition occurs due to diarrhea or intestinal infections or during therapy with medicines, including chemotherapy or antibiotics.

It is a spore-forming good bacteria that helps in rebalancing the intestine. It also treats or prevents various medical conditions associated with gut imbalance. 

Uses of Bacillus Clausii Spores Suspension

Bacillus Clausii Spores Suspension Uses
  • Bacillus clausii is primarily used to treat acute diarrhea in children and young people.
  • It comes under the group of probiotic drugs. 
  • It is also used for preventing antibiotic-associated diarrhea, treating symptoms of IBS (irritable bowel syndrome) including bloating, boosting immunity, abdominal pain, diarrhea, or constipation, and preventing recurrent respiratory tract infections in children prone to them.

How Does Bacillus Clausii Spores Suspension Work?

  • Bacillus clausii is a probiotic medicine that contains live bacteria that are beneficial for health.
  • When taken, the Bacillus Clausii spores survive the acidic environment of the stomach and reach the intestines, where they become active vegetative cells.
  • These active cells compete with harmful pathogenic bacteria in the gut, preventing their growth and attachment to the gut walls.

Side Effects of Bacillus Clausii Spores Suspension

Here are some common side effects noticed after taking Bacillus Clausii Spores Suspension: 

  • Gas
  • Bloating
  • Nausea or vomiting
  • Stomach discomfort
  • Allergic reactions like rash or itching

Precaution Bacillus Clausii Spores Suspension

Here are some precautions that should be taken by you before taking the medicine: 

  • Completely avoid taking Bacillus clausii along with any kind of steroids (medications that weaken the immune system), it may increase the risk of getting sick.
  • Take Bacillus Clausii at least 2 hours before or after antibiotics because taking Bacillus Clausii along with the antibiotics can reduce their effectiveness. 
  • Tell your doctor, if you want to conceive, pregnant, and breastfeed women.
  • Also tell your doctor if you take other medical treatments or medical history, and have liver, or kidney disease. 

What if You miss a dose?

  • If by chance you miss a dose, take it as soon as possible before the time of the next dose. Give at least a 4-5 hours gap between the two doses, if you are near to the next dose time then don’t take your first dose and take the next dose on time. 
  • If you take the medicine as an overdose by accident and experience extreme side effects or symptoms like digestive discomforts such as bloating and gas. If you observe these symptoms persistently, immediately consult your doctor to avoid any serious condition.
  • Do not take double or twice doses together, no doctor or any medical expert is recommended in this condition. 

Where should You keep Your medication?

  • Store the Bacillus Clausii spore suspension at a temperature of 2–8°C to maintain spore viability.
  • Do not freeze the medicine to prevent damage to the spores.
  • Do not place the medicine under direct sunlight, heat, and moisture. 
  • Always keep the bottle in a tight container or original bottle to store it well. 
  • Do not keep the syrup in the freezer or an extremely cold place. 
  • Keep it out of reach of children and store it safely where kids can’t reach. 

Experts Advise or Drug Warnings 

Here are some important points you should consider before taking the medicine: 

  • Avoid taking Bacillus Clausii medicine if you have any kind of allergic problems. 
  • Tell your doctor if you are suffering from a serious illness or disease. 
  • Also, tell your doctor if you are pregnant or breastfeeding women. 
  • Give the medicine to children only prescribed by the doctor. 

Diet & Lifestyle Advice

  • Drink more water to stay hydrated and maintain a water level that is high enough in your body.
  • Take more fiber-rich food including whole grains, lentils, broccoli, beans, and peas.
  • Try to avoid stress by doing physical activities, meditation, and yoga.
  • Take proper rest and get proper sleep.

Frequently Asked Questions

Ques. What is the use of Bacillus Clausii?

Ans. Bacillus Clausii is used to treat imbalances of intestinal bacterial flora caused by diarrhea or during therapy with medicines such as antibiotics and chemotherapy. Also, it helps in the absorption of nutrients and the correction of avitaminosis.

Ques. Is Bacillus Clausii a steroid?

Ans. No, the medicine is not a steroid and it is a strain of probiotic bacteria.

Ques. Does Bacillus Clausii have any effect on sleep?

Ans. The medicine is not mainly caused by affecting sleep and primarily functions in the digestive system and has no side effects on sleeping or circadian rhythms.

Ques. Can I take Bacillus Clausii for longer durations?

Ans. No, don’t take the medicine for a long duration unless advised by the doctor or your health care experts.

Ques. How much time does Bacillus Clausii take to work?

Ans. The medicine shows its effect according to the medical conditions. In the treatment of acute diarrhea, improvements are typically seen 1-3 days after taking the medicine.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Bacillus Clausii Spores Suspension, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Deflazacort 6mg Tablets Uses, Side Effects, Precautions

Deflazacort 6mg Tablets: Uses, Side Effects, Precautions and More

Deflazacort tablets are used to treat DMD in children aged 2 or older and adults with the same disease. DMD is the abbreviation for Duchenne muscular dystrophy, a progressive disease characterized by muscular degradation and weakness. The medication works by reducing inflammation and modulating the immune system’s activity. 

What is DMD Or Duchenne Muscular Dystrophy?

Duchenne muscular dystrophy (DMD) is a genetic disorder. The key characteristics of this disease are progressive degeneration of muscles and weakness of muscles. This disease/disorder is due to a lack of a protein called dystrophin. This protein helps keep muscle cells intact. 

The chemical composition of the medication is as follows,

Deflazacort 6mg Tablets Chemical Structure
Chemical name C₂₅H₃₁NO₆
IUPAC name(11β,16β)-21-(Acetyloxy)-11-hydroxy-2′-methyl-5′H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione

How Do Deflazacort 6mg Tablets  Work?

Deflazacort 6mg Tablets Uses

Deflazacort Tablets are a prodrug. This means that while it is administered in its inactive form, the body converts it into its active form. The active form of this compound is 21-desacetyldeflazacort.

Deflazacort Tablets are a corticosteroid and it works by mimicking the effects of cortisol in the human body. Cortisol is a natural hormone that is produced in the body by the adrenal glands. It works by intervening in the production of enzymes and chemicals in the body that lead to inflammation and is a part of the immune system’s response to various foreign invaders in the body. 

Ways in which Deflazacort Tablets Reduce Inflammation 

One of how it helps reduce inflammation in the body is by reducing the production of pro-inflammatory cytokines. These cytokines are chemicals produced in the body that are responsible for increased inflammation. Deflazacort tablets reduce the production of such compounds in the body. An example of the pro-inflammatory cytokines is interleukins. Deflazacort tablets, by reducing the production of such compounds in the body, tone down the inflammatory response of the body. 

Deflazacort tablets further help in reducing inflammation by reducing the activity of the white blood cells that are responsible for inflammation. These are neutrophils and macrophages. 

Another way in which it blocks or reduces the inflammatory response of the body is by inhibiting the pathway for the production of arachidonic acid, which is a precursor to various inflammatory compounds. These compounds are responsible for the sensation of pain as well. 

Deflazacort tablets are used for the treatment of autoimmune diseases as these tablets suppress the immune system response by reducing the activity of lymphocytes. The suppression of lymphocytes is important in the case of autoimmune diseases as in the case of autoimmune diseases, the lymphocytes attack the body’s tissues. 

Two additional ways in which deflazacort tablets reduce inflammation are as follows, 

  • It decreases the release of inflammation-causing enzymes by stabilizing the membrane of the cells that release inflammation-causing enzymes. The medication stabilizes lysosomal
  • Secondly, it decreases the capillary permeability. This decreased permeability helps reduce swelling and redness associated with inflammation. 

How are Deflazacort 6mg Tablets different from other Corticosteroids

 Deflazacort Tablets are different from others and are considered a “prodrug,” meaning it is metabolized in the liver into their active form. It has a slightly different side effect profile compared to other corticosteroids, with potentially lower risks of certain side effects, such as bone density loss, due to its weaker mineralocorticoid activity.

By modulating the immune and inflammatory responses, deflazacort provides symptomatic relief and helps manage chronic conditions. However, its use must be carefully monitored due to potential side effects such as weight gain, hyperglycemia, and adrenal suppression.

What are deflazacort tablets Used for?

Deflazacort tablets are used for the treatment of DMD. While it is primarily approved for treating DMD, it has been used off-label for various conditions due to its anti-inflammatory and immunosuppressive properties. These conditions include:

  • Rheumatoid arthritis
  • Asthma
  • Crohn’s disease
  • Ulcerative colitis
  • Systemic lupus erythematosus
  • Nephrotic syndrome
  • Dermatomyositis
  • Polymyalgia rheumatica
  • Sarcoidosis
  • Idiopathic thrombocytopenic purpura

It’s important to note that the use of deflazacort for these conditions should be under the guidance of a healthcare professional.

Prescription Considered While Taking Deflazacort

The dosage of this medication depends upon the treatment plan made by the doctor. Some of the factors that the doctor may consider while prescribing this medication are – 

  • The age of the patient
  • How the individual is responding to the therapy 
  • The condition for which the individual is being treated. 

Note: For the best results, it is important to follow the instructions of your doctor as precisely as possible.  

 Deflazacort Tablets – What’s Unheard About It? 

Deflazacort is a medication that was patented in 1969 and was approved for treatment in 1969. The initial trade name of this medication was Calcort.

Deflazacort 6mg Tablets – Side Effects

Some of the most common side effects of Deflazacort 6mg Tablets include the face of the patient appearing more round in shape. It can also lead to weight gain and an increase in appetite. 

Like other corticosteroids, deflazacort may suppress the immune system, potentially increasing the risk of infections. Long-term use can lead to decreased bone density, growth retardation in children, and other systemic effects. It can also lead to delayed healing of wounds along with hormonal changes and potentially stunted growth in children. There are some additional side effects besides the ones that are already listed. These are – 

  • Excessive hair growth on the face
  • Central obesity,
  • Polyuria,
  • Constipation,
  • Irritability,
  • Fever,
  • Back pain, 
  • Erythema (skin redness),
  • Rash,
  • Nausea,
  • Nosebleeds,
  • Stretch marks

Patients should be monitored regularly by their healthcare provider to manage and mitigate potential adverse effects.

It is important to discuss pre-existing health conditions before taking Deflazacort tablets along with monitoring and taking vitamin D supplements if this supplement is prescribed by the doctor. This medication should not be discontinued abruptly. 

Deflazacort Tablets – Severe Side Effects

In case the patient experiences any one of the following severe side effects, a doctor should be contacted on an urgent basis. These severe side effects are – 

  • Severe mood changes or confusion.  
  • Signs of infection (fever, chills).  
  • Severe stomach pain or bloody stools.  
  • Vision changes or swelling in the legs.

Frequently Asked Questions

Ques. Is Deflazacort tablets steroid?

Ans Yes,  Deflazacort tablets are steroids.

Ques. What are Deflazacort tablets used for?

Ans They are primarily used for the treatment of DMD but can be used for the treatment of other diseases as well.

Ques. What are Deflazacort tablets 6 mg used for?

Ans They are used for the treatment of DMD.

Ques. Can Deflazacort tablets be taken with alcohol?

Ans No, they should not be taken with alcohol.

Ques. Are deflazacort tablets for skin infections?

Ans Yes, doctors sometimes prescribe these tablets for off-label use to treat skin infections such as skin psoriasis.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Aceclofenac & Paracetamol Tablets, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Aceclofenac & Paracetamol Tablets Uses, Benefits, Side Effects, Doses, Precautions and More

Aceclofenac & Paracetamol Tablets: Uses, Benefits, Side Effects, Doses, Precautions and More

Aceclofenac Paracetamol tablets are designed to address concerns of headaches, mild migraine, muscle pain, dental pain, inflammation, and fever. This tablet is a combination of two active ingredients that work together to provide relief from pain and inflammation associated with various conditions. 

Aceclofenac Paracetamol tablets consist of two active ingredients that work together to provide relief from pain and inflammation associated with various conditions. 

The composition of this medicine is as follows,

Aceclofenac
Chemical formula C16H13Cl2NO4
IUPAC name 2-[(2,6-Dichlorophenyl) amino] phenylacetoxyacetic acid
Paracetamol
Chemical FormulaC8H9NO2
IUPAC nameN-(4-hydroxyphenyl)acetamide

What are the Uses of Aceclofenac and Paracetamol Tablets?

Aceclofenac & Paracetamol Tablets Uses

The main use of this generic tablet is pain relief. This medication usually treats a few specific conditions and diseases. These conditions are as follows. 

Pain and Inflammation In Musculoskeletal Disorders 

Some of the musculoskeletal conditions for which this medication is prescribed are –

  •    Osteoarthritis 
  •    Rheumatoid Arthritis 
  •    Ankylosing Spondylitis 

Conditions With Acute Pain 

There are a few short-term conditions for which Aceclofenac Paracetamol tablets are prescribe. These are 

  •    Dental pain 
  •    Postoperative pain
  •    Lower back pain 
  •    Soft tissue injury 

Chronic Pain With Inflammation 

This medication is used for the treatment of chronic and painful conditions such as gout and frozen shoulder. Gout is caused by the inflammation caused by the build-up of uric acid in the body and is considered a type of arthritis. Frozen shoulder is a disease in which there is pain and stiffness in the shoulder joint. As a result, patients suffering from this condition often have difficulty moving their shoulders. 
Fever With Pain  

Patients experiencing both fever and pain use it. An example of such a case is when a person has got flu. 

Anti-inflammatory And Pain Relief 

It is use for reducing pain and inflammation in medical conditions including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

How Does Aceclofenac & Paracetamol Work?

Each of the two components in the medication has a role to play in reducing pain and inflammation. 

Aceclofenac: This is a nonsteroidal anti-inflammatory drug (NSAID).  This works by interfering with the synthesis of the compounds associated with pain and inflammation. Prostaglandins is the compound in the human body that is responsible for pain, and inflammation and is synthesized by the cyclooxygenase (COX) enzymes. Aceclofenac inhibits the production of cyclooxygenase (COX) enzymes in the body. 

Paracetamol is a pain reliever and a fever-reduction medication. It helps regulate body temperature and reduces the production of compounds that are responsible for pain in the body. 

Aceclofenac & Paracetamol Side Effects

Some of the most common side effects include – 

  • Nausea 
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Dizziness
  • Elevated liver enzymes

Serious side effects from this medication are rare. Serious side effects include allergic reactions and kidney and liver damage. 

Precautions 

  • Avoid using this medication if the patient is allergic to the non-steroidal anti-inflammatory (NSAIDs) category of drugs. 
  • Avoid this medication if the patient is known to have an allergic reaction to paracetamol. 
  • Further, higher doses of this medication can damage the liver or kidney. 
  • Do not consume alcohol with this medication. 

Interactions

This medication can interact with other medications such as anticoagulants, other NSAIDs, and certain antihypertensives. In case an individual or a patient is on any of these medications, aceclofenac paracetamol tablets should be avoid. This medication is also not suitable for people with liver and kidney issues. Seek the guidance of a healthcare provider when it comes to taking this medication. 

Advice Regarding Dosage

“Adults can take one tablet twice a day. The patient should ideally take this medication with food to minimize gastrointestinal discomfort. Doctors do not recommend this medication for children due to a lack of clinical data. When it comes to the elderly, the dosage depends upon the doctor. The doctor will decide the dosage of the medication depending on the individual’s health status. 

Frequently Asked Questions

Ques. What are aceclofenac + paracetamol tablet brands?

Ans. Here are some brands of aceclofenac and paracetamol tablets: 
1. Zerodol P: By Ipca Laboratories Ltd
2. Hifenac P: By Intas Pharmaceuticals Ltd
3. Aceclo Plus: By Aristo Pharmaceuticals Pvt Ltd
4. Parafast: By Cipla Ltd
5. Dolowin-Plus: By Micro Labs Ltd

Ques. Who should avoid these tablets?

Ans. People who have pre-existing conditions such as liver or kidney conditions should avoid these medications. Further, people who are taking anticoagulants or are allergic to this type of medication should avoid these tablets.  

Ques. Can this medication be taken on an empty stomach? 

Ans. No, this medication should only be taken after a meal as taking this medication on an empty stomach can cause stomach issues such as stomach ulcers.

Ques. Can Aceclofenac and Paracetamol tablets be used long-term?

Ans. No, this medication can’t be used long-term as long-term use of this medication can lead to liver and kidney damage. Use them only for the necessary duration.

Ques. Can these tablets be taken with other medications?

Ans. You should discuss this with a doctor first. This medication does interact with other drugs such as blood thinners and other paracetamol-containing drugs.

Ques. What should I do if I miss a dose?

Ans. Do not try to overcompensate the dosage. If you have missed one dose and it is already time for the next one, then don’t take the missed one. There should be a 4-6-hour gap between the two doses.

Disclaimer

We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Aceclofenac & Paracetamol Tablets, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Rabeprazole Sodium and Domperidone Capsules Uses, Side Effects, Doses, and Benefits

Rabeprazole Sodium and Domperidone Capsules Uses, Side Effects, Doses, and Benefits

Rabeprazole Sodium and Domperidone Capsules are used to treat symptoms of gastrointestinal reflux due to stomach ulcer (Peptic ulcer disease), hyperacidity, and Zolllinger-Ellison syndrome (overproduction of acid due to a pancreatic tumor).

It is also the most effective capsule to treat gastroesophageal reflux disease (GERD) symptoms. It is a medical condition in which the sphincter (valve) at the uppermost organ of the stomach gets hurt or is damaged, irritated, and not working properly due to acid production over the need. This extra production of acid results in juice and acid flowing into the food pipe causing stomach upset, pain, heartburn, and irritation in the stomach.

Rabeprazole Sodium and Domperidone Capsules Chemical Structure

Rabeprazole Sodium and Domperidone Capsules Uses

Rabeprazole sodium and domperidone capsules are mainly used to treat medical conditions like Gastrointestinal Disorders, stomach pain, acidity, and excessive acid production in the digestive system.

  • Treating Acid Reflux and Stomach Ulcers: The most common use of rabeprazole and domperidone is to manage the acid reflux condition in the stomach also called gastroesophageal reflux disease (GERD). It works by decreasing the production of acid and increasing gastric emptying, that combination helps to prevent acid from irritating the esophagus.

Moreover, these capsules are effective in treating stomach and duodenal ulcers. It slows down the rate of acid production and prevents ulcers in the stomach and mouth. 

Rabeprazole Sodium and Domperidone Capsules Uses
  • Alleviating Symptoms of Nausea: Domperidone has the properties of an antiemetic and that combination is used for individuals who suffer from nausea as part of their gastrointestinal disorder. It is also recommended for those patients undergoing treatment that can reduce nausea, including chemotherapy, and gastroparesis medical conditions. In these conditions an empty stomach results in vomiting and discomfort. 
  • Usage in Pregnancy: The rabeprazole sodium and domperidone capsules used in pregnancy are very sensitive topics and are always taken with careful consideration by the medical practitioner. Normally, this medicine is avoided in pregnancy due to potential risks to the developing fetus. Always consult the doctor before taking this medicine and use it with proper guidance of healthcare during pregnancy.

How Do Rabeprazole Sodium and Domperidone Capsules Work?

Rabeprazole is a proton pump inhibitor (PPI). Its main function is reducing excess acid in the stomach by inhibiting the actions of an enzyme (H+/K+ ATPase). This enzyme lies in the wall of cells that is responsible for gastric acid secretion and damaging tissues in the stomach, food pipe, and duodenum. It results in patients getting relief from acidity and acid problems indigestion, and heartburn. 

Domperidone is a D2 receptor antagonist and Prolactin releases and acts on the upper stomach. It accelerates the mobility or movement of the gastrointestinal tract. Also, it reduces the chances of vomiting in the center (chemoreceptor trigger zone-CTZ). Due to this, food easily moves through the pipe and stomach. This medicine is also used sometimes to increase the milk supply in women’s bodies. 

Both of the drugs work together and treat the medical conditions of gastrointestinal reflux disease (GERD) and peptic ulcers.

Note: Use Rabeprazole Sodium and Domperidone Capsules only prescribed by the Doctor or medical expert. 

Rabeprazole Sodium and Domperidone CapsulesSide Effects 

  • Nausea or vomiting
  • Back pain
  • Diarrhea, constipation, stomach pain, flatulence
  • Cough, sore throat, runny nose
  • Insomnia (difficulty in sleeping)
  • Weakness or loss of strength
  • Flu-like symptoms
  • Dry mouth
  • Headache, dizziness
  • Benign polyps in the stomach

Precautions for Rabeprazole Sodium and Domperidone Capsules

Here are some important precautions for Rabeprazole Sodium and Domperidone Capsules to treat the above disorders effectively:

  • Take it as prescribed by the doctor as per the time and dose.
  • Domperidone + Rabeprazole is used for the treatment of acidity and heartburn.
  • Take it at least one hour before the meal and most preferably in the morning.
  • Inform the doctor if you are facing any other disease or have any other treatment.
  • Also tell your health care or doctor if you have a fever, watery diarrhea, or stomach pain.
  • If you face any irregularity or irritation after taking this medicine, immediately inform or consult your doctor.
  • The use of it for the long term resulted in weak bones and a deficiency of minerals like magnesium.
  • Take a proper diet and increase intake of calcium and magnesium or their supplements are recommended by the doctors and your health care advisor. 

What if You miss a dose and Overdose Rabeprazole Sodium and Domperidone Capsules?

If you miss one or two doses of this combination may not cause any side effects or create any problems. However, take it as soon as possible with the guidance of the doctor but try to avoid taking two doses together.

In any case, if you take this combination as an overdose, it may cause somnolence, agitation, disorientation, altered consciousness, and extrapyramidal reactions. Immediately tell your doctor about the overdose of medicine and take proper advice. 

How to Store Rabeprazole Sodium and Domperidone Capsules?

  • Keep Rabeprazole Sodium and Domperidone capsules in a cool and dry place and at the room temperature range of 15°C to 30°C (59°F to 86°F). 
  • Always keep away from direct sunlight, heat, and moisture. 
  • Keep containing it in an original package to prevent humidity and air exposure. 
  • Keep away from the children and avoid any risk of accidental ingestion. 

Drug Warnings/ Experts Advice

  • Avoid alcohol if you take Domperidone + Rabeprazole capsules.
  • A person who is facing gastroesophageal reflux disease should follow the proper diet and lifestyle, incorporating dietary changes according to the GERD-friendly diet. It is a special kind of diet that mainly emphasizes low-acid foods, avoidance of spicy and fatty meals, and reduction of portion sizes.
  • Always take this combination before the meal for best results.

Frequently Asked Questions

Ques. What are the contraindications of Domperidone+Rabeprazole?

Ans. Domperidone+Rabeprazole is harmful to those patients who are suffering from hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the drugs. It is also cautiously advised for patients who have kidney or liver disease.

Ques.  Is it safe to use Domperidone+Rabeprazole?

Ans. Yes, Domperidone and Rabeprazole are safe for most of the patients. However, it shows a few side effects in some patients such as stomach pain, diarrhea, dryness in the mouth, flatulence, dizziness, and headache. The most important advice is if you experience any uncommon side effects immediately consult your doctor. 

Ques. Can the use of Domperidone+Rabeprazole cause abnormal heartbeat?

Ans. Yes, Domperidone+Rabeprazole can increase the rate of heartbeat or develop irregular heartbeats (serious arrhythmias). It is considered the most serious side effect of this medicine but the chances of this happening are very low. However, the risk of this happening is higher if you are 60 or older.

Ques. What is the best time to take Domperidone+Rabeprazole?

Ans. The best time to take Domperidone+Rabeprazole is empty stomach or before your first meal.

Ques. Whether Rabeprazole and Domperidone can be taken for heartburn relief?

Ans. Yes, Rabeprazole and Domperidone can reduce heartburn, gastroesophageal reflux disease (GERD), or peptic ulcer.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Rabeprazole Sodium and Domperidone Capsules, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Deflazacort Tablets Uses, Side Effects, Precautions and More

Deflazacort Tablets: Uses, Side Effects, Precautions and More

Deflazacort Tablets Tablets are used to treat DMD in children aged 2 or older and adults with the same disease. DMD is the abbreviation for Duchenne muscular dystrophy, a progressive disease characterized by muscular degradation and weakness. The medication works by reducing inflammation and modulating the immune system’s activity. 

What is DMD Or Duchenne Muscular Dystrophy?

Duchenne muscular dystrophy (DMD) is a genetic disorder. The key characteristics of this disease is progressive degeneration of muscles and weakness of muscles. This disease/disorder is due to a lack of a protein called dystrophin. This protein helps keep muscle cells intact. 

The chemical composition of the medication is as follows, 

Chemical name C₂₅H₃₁NO₆
IUPAC name(11β,16β)-21-(Acetyloxy)-11-hydroxy-2′-methyl-5′H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione
Deflazacort Chemical Structure

How Do Deflazacort Tablets Work?

Deflazacort Tablets are a prodrug. This means that while it is administered in its inactive form, the body converts it into its active form. The active form of this compound is 21-desacetyldeflazacort.

Deflazacort Tablets are a corticosteroid and it works by mimicking the effects of cortisol in the human body. Cortisol is a natural hormone that is produced in the body by the adrenal glands. It works by intervening in the production of enzymes and chemicals in the body that lead to inflammation and is a part of the immune system’s response to various foreign invaders in the body. 

Ways in which Deflazacort Tablets Reduce Inflammation

One of how it helps reduce inflammation in the body is by reducing the production of pro-inflammatory cytokines. These cytokines are chemicals produced in the body that are responsible for increased inflammation. Deflazacort tablets reduce the production of such compounds in the body. An example of the pro-inflammatory cytokines is interleukins. Deflazacort tablets, by reducing the production of such compounds in the body, tone down the inflammatory response of the body. 

Deflazacort tablets further help in reducing inflammation by reducing the activity of the white blood cells that are responsible for inflammation. These are neutrophils and macrophages. 

Another way in which it blocks or reduces the inflammatory response of the body is by inhibiting the pathway for the production of arachidonic acid, which is a precursor to various inflammatory compounds. These compounds are responsible for the sensation of pain as well. 

Deflazacort tablets are used for the treatment of autoimmune diseases as these tablets suppress the immune system response by reducing the activity of lymphocytes. The suppression of lymphocytes is important in the case of autoimmune diseases as in the case of autoimmune diseases, the lymphocytes attack the body’s tissues. 

Two additional ways in which deflazacort tablets reduce inflammation are as follows, 

  • It decreases the release of inflammation-causing enzymes by stabilizing the membrane of the cells that release inflammation-causing enzymes. The medication stabilizes lysosomal
  • Secondly, it decreases the capillary permeability. This decreased permeability helps reduce swelling and redness associated with inflammation. 

How are Deflazacort Tablets different from Other Corticosteroids

 Deflazacort Tablets are different from others and are considered a “prodrug,” meaning it is metabolized in the liver into their active form. It has a slightly different side effect profile compared to other corticosteroids, with potentially lower risks of certain side effects, such as bone density loss, due to its weaker mineralocorticoid activity.

By modulating the immune and inflammatory responses, deflazacort provides symptomatic relief and helps manage chronic conditions. However, its use must be carefully monitored due to potential side effects such as weight gain, hyperglycemia, and adrenal suppression.

What are Deflazacort Tablets Used for?

What are Deflazacort Tablets Used for

Deflazacort tablets are used for the treatment of DMD. While it is primarily approved for treating DMD, it has been used off-label for various conditions due to its anti-inflammatory and immunosuppressive properties. These conditions include:

  • Rheumatoid arthritis
  • Asthma
  • Crohn’s disease
  • Ulcerative colitis
  • Systemic lupus erythematosus
  • Nephrotic syndrome
  • Dermatomyositis
  • Polymyalgia rheumatica
  • Sarcoidosis
  • Idiopathic thrombocytopenic purpura

It’s important to note that the use of deflazacort for these conditions should be under the guidance of a healthcare professional. 

Prescription Considered While Taking Deflazacort

The dosage of this medication depends upon the treatment plan made by the doctor. Some of the factors that the doctor may consider while prescribing this medication are – 

  • The age of the patient
  • How the individual is responding to the therapy 
  • The condition for which the individual is being treated. 

Note: For the best results, it is important to follow the instructions of your doctor as precisely as possible. 

 Deflazacort Tablets – What’s Unheard About It? 

Deflazacort is a medication that was patented in 1969 and was approved for treatment in 1969. The initial trade name of this medication was Calcort.

Deflazacort Tablets – Side Effects

Some of the most common side effects of these tablets include the face of the patient appearing more round in shape. It can also lead to weight gain and an increase in appetite. 

Like other corticosteroids, deflazacort may suppress the immune system, potentially increasing the risk of infections. Long-term use can lead to decreased bone density, growth retardation in children, and other systemic effects. It can also lead to delayed healing of wounds along with hormonal changes and potentially stunted growth in children. There are some additional side effects besides the ones that are already listed. These are – 

  • Excessive hair growth on the face
  • Central obesity,
  • Polyuria,
  • Constipation,
  • Irritability,
  • Fever,
  • Back pain, 
  • Erythema (skin redness),
  • Rash,
  • Nausea,
  • Nosebleeds,
  • Stretch marks

Patients should be monitored regularly by their healthcare provider to manage and mitigate potential adverse effects.

It is important to discuss pre-existing health conditions before taking Deflazacort tablets along with monitoring and taking vitamin D supplements if this supplement is prescribed by the doctor. This medication should not be discontinued abruptly. 

Deflazacort Tablets – Severe Side Effects

In case the patient experiences any one of the following severe side effects, a doctor should be contacted on an urgent basis. These severe side effects are – 

  • Severe mood changes or confusion.  
  • Signs of infection (fever, chills).  
  • Severe stomach pain or bloody stools.  
  • Vision changes or swelling in the legs.

Frequently Asked Questions

Ques. Is Deflazacort tablets steroid?

Yes,  Deflazacort tablets are steroids.

Ques. What are Deflazacort tablets used for?

They are primarily used for the treatment of DMD but can be used for the treatment of other diseases as well.

Ques. What are Deflazacort tablets 6 mg used for?

They are used for the treatment of DMD.

Ques. Can Deflazacort tablets be taken with alcohol?

No, they should not be taken with alcohol.

Ques. Are deflazacort tablets for skin infections?

Yes, doctors sometimes prescribe these tablets for off-label use to treat skin infections such as skin psoriasis.

Montelukast Sodium and Levocetirizine Hydrochloride Tablets Uses, Side Effects, Doses, and Benefits

Montelukast Sodium and Levocetirizine Hydrochloride Tablets: Uses, Side Effects, Doses, and Benefits

Montelukast Sodium and levocetirizine hydrochloride medicine are a combination of two salts that are used to treat allergies including hay fever, runny nose, skin allergy, and sneezing conditions. Both drugs work in different ways, Montelukast sodium salt works by blocking leukotrienes, chemicals of allergic reactions. 

Montelukast Sodium and Levocetirizine Hydrochloride Tablets Uses, Side Effects, Doses, and Benefits

Note: Montelukast Sodium and Levocetirizine Hydrochloride Tablets should be taken as per the dose and duration as recommended by the doctor or medical professional.

Levocetirizine hydrochloride acts as an antihistamine that decreases the symptoms such as nose running, itching, and sneezing, A combination of both salt tablets gives relief from allergy and itching symptoms, helps to improve breathing, and enhances the quality of an individual’s life from allergy.

Molecular formula: C 21h 25clN 2o 32HCl; Molecular weight: 461.82; Specification: specification is mostly 5mg. The dosage form is all oral formulations and has tablets, granules, capsules, etc.

Montelukast Sodium and Levocetirizine Hydrochloride Tablets Uses

Montelukast Sodium and Levocetirizine Hydrochloride Tablets uses

Here are some important points where we can use  Montelukast Sodium and Levocetirizine Hydrochloride Tablets:

  • Allergic Rhinitis: Use to treat allergic conditions like runny nose, itchy eyes, and sneezing. 
  • Asthma Management: To cure asthma by reducing inflammation of airways like the nose and lungs. 
  • Seasonal Allergies: Also help to prevent seasonal diseases such as nasal congestion and sneezing. 

How Does Montelukast Sodium and Levocetirizine Hydrochloride Work?

Montelukast Sodium salt works by blocking certain chemicals such as leukotrienes in the body that cause bronchoconstriction, narrowing of the airways, inflammation, and allergic conditions. It also helps to prevent asthma attacks and eliminate the allergic infected cells. 

Levocetirizine Hydrochloride is an antihistamine agent that works by blocking histamine substances. Histamine substances cause sneezing, itching, and nose running. 

Together, both medicines help to cure and hive relieve allergic symptoms and asthma attacks. 

Side Effects of Montelukast Sodium and Levocetirizine Hydrochloride Tablet 

Here are all the side effects of this medicine and this medicine is always prescribed by the doctor after reviewing the benefits are more than the side effects. A list of the common side effects are:

  • Diarrhea
  • Dryness in mouth
  • Nausea
  • Fatigue
  • Headache
  • Skin rash
  • Sleepiness
  • Vomiting
  • Fever
  • Abdominal pain
  • Increased liver enzymes
  • Upper respiratory tract infection
  • Sore throat

Despite all the mentioned side effects, the most common side effect is dry mouth after taking Montelukast 10mg + Levocetirizine 5mg Tablet. To counter this condition, you can frequently mouth rinses, and increasing your intake of water can help you. The above-mentioned side effects don’t require any medical help or tablets but need to visit to doctor if these side effects are at a high rate. 

Precautions for Montelukast Sodium and Levocetirizine Hydrochloride Tablet

Here are precautions for Montelukast Sodium and Levocetirizine Hydrochloride Tablet:

  • Allergic Reactions: Try to avoid if you have any kind of allergy and immediately contact your doctor for any allergic symptoms like rashes on the skin, or facing difficulty breathing.
  • Liver and Kidney Issues: Use this medicine only by prescription of a doctor if you have kidney disease and take only the required dose.
  • Pregnancy and Breastfeeding: If you are pregnant or breastfeeding women, consult your doctor before taking this medicine to make sure it is safe for your baby.
  • Mental Health Effects: This medicine may cause emotional changes or affect mental health such as anxiety or depression. Take advice from your doctor before taking this medicine.
  • Drowsiness: This medicine causes drowsiness and tries to avoid doing any kind of activity which need to requires concentration.
  • Drug Interactions: Tell your doctor if you have any other medicine course running.
  • Asthma Management: This drug is not the cure for Asthma attacks always take your inhaler or medicine as directed.
  • Child and Adolescent Use: Don’t give this medicine to children without consulting a doctor.
  • Avoid Alcohol: Try to avoid alcohol while taking this tablet and don’t intake any kind of intoxication.

What if You Miss a Dose or Overdose of the Medicine?

  • There are no issues if you missed your one-time dose but take it as soon as possible before the time for the next dose.
  • Overdose of this drug may reflect symptoms like sleepiness, vomiting, headache, thirst, and abdominal pain. 

How Do You Store Montelukast Sodium and Levocetirizine Hydrochloride Tablets?

  • Store this medicine at room temprature of 20°C to 25°C or 68°F to 77°F.
  • Keep this medicine in its original package to prevent moisture and humidity.
  • Store away from the heat and sun radiations.
  • Keep away from the reach of children and pets.
  • Do not store this medicine in a freezer or in extremely cold temperatures.
  • Always check the expiration date before taking medicine and never take expired dated tablets. 

Frequently Asked Questions

Ques. What is Levocetirizine + Montelukast medicine?

Ans. Levocetirizine+Montelukast is a mixture of two drugs which are Montelukast and Levocetirizine. The combination of both medicines will cure allergic symptoms like eye irritation, itching, nose running, sneezing, and asthma attacks.

Ques. Can Montelukast Sodium and Levocetirizine Hydrochloride medicine be stopped when allergy symptoms are relieved?

Ans. No, Montelukast Sodium and Levocetirizine Hydrochloride medicine continued as per the doctor’s advice. If you face an extreme or worsened condition of allergic symptoms s then immediately consult your doctor for re-evaluation.

Ques.  Can I drink alcohol while taking Montelukast Sodium and Levocetirizine Hydrochloride tablets?

Ans. No, do not take alcohol or any intoxicating substance after taking Montelukast Sodium and Levocetirizine Hydrochloride tablets. Alcohol increases the severity of drowsiness/sleepiness which causes many unfortunate situations.

Ques. Will Levocetirizine+Montelukast be more effective if taken in higher doses?

Ans. No, a high dose of this medicine will not affect more, and it is also not recommended by any doctor. Taking the medicine as per the doctor’s prescriptions.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Montelukast Sodium and Levocetirizine Hydrochloride tablets, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Also Read – Nimesulide Tablet Uses

Nimesulide Tablet Uses, Side Effects and Precautions

Nimesulide Tablet Uses, Side Effects and Precautions

Nimesulide (NSAID) is a non-steroidal anti-inflammatory drug, which is a pain relief and fever prevention medication. It also helps in relieving acute pain, little symptomatic osteoarthritis treatment, and basic dysmenorrhoea in adolescents and adults above 12 years old. 

It is an inhibitor of cyclooxygenase that will eliminate the symptoms efficiently. This medicine targets all components and slats including free radicals, histamine, cyclooxygenases, proteolytic enzymes, and prostaglandin that lead to the development of swelling.

Nimesulide Tablet Chemical Formula
Chemical FormulaC13H12N2O5S
SummaryNimesulide is a cyclooxygenase 2 inhibitor that is used to relieve acute pain and primary dysmenorrhea. 
Molar Mass308.31 g·mol−1
Generic Name Nimesulide
DrugBank Accession NumberDB04743

Nimesulide Tablet Uses

Nimesulide Tablet Uses

Nimesulide 100mg + paracetamol 325 mg slats is a strong combination of two medicines by the brand name “NIMOSET-P”. It is available in the form of a tablet in a pack of 10*10 Blister size. NIMOSET-P tablets are recommend by General physicians, Gynecologists for periods of pain, Orthopedics, Dentists, and ENT specialists. 

It is also used for relieving various kinds of pains including muscle pain, headaches, dental pain, mild migraine, ankylosing spondylitis, rheumatoid arthritis, and osteoarthritis pain. 

Nimesulide Side Effects

Nimesulide tablet is always take by the prescription of a professional or qualified medical person. If you use it in the long term, may it cause harm to the liver or result in significant side effects such as gastrointestinal bleeding or renal issues. Here are some significant effects of Nimesulide: 

  • Acid or sour stomach
  • Blood clotting problems
  • Dizziness
  • Nausea and vomiting
  • Skin infection
  • Stomach pain and cramps
  • Increased liver enzymes
  • Diarrhoea

If you feel any irritation or unbearable symptoms, immediately contact your doctor for guidance. Nonetheless, if you see any side effects from Nimesulide, stop taking these tablets. Take the medicines, after taking the doctor’s assessment of your condition and medical situations. Never take these medicines without a prescription from medical experts. 

How Does It Work?

NIMOSET-P is the combination of Nimesulide and paracetamol. This combination of medicines is mainly use for the prevention of specific chemical messengers that produce inflammation, fever (redness and swelling), and discomfort. It works as a pain and fever reliever.

Indications

NIMOSET-P: It is the combination of two salts of NIMESULIDE 100MG PARACETAMOL 325 MG pill use for the treatment of pain and inflammation. This medicine or tablet is for low back pain, osteoarthritis, tooth pain, rheumatoid arthritis, post-operative pain, and trauma. 

Precautions should be taken for Nimesulide Tablets 

Before taking Nimesulide tablets, take advice from doctors or medical experts. If you have any irritation, allergies, or unbearable symptoms immediately contact your doctor.

  • Nimesulide tablets do not allow the intake of alcohol, other harmful drugs, or coagulation issues, in pregnant women, children, or nursing mothers.  
  • It is not allowed for those patients who have asthma, heart disease, recent gastrointestinal bleeding, recent heart bypass surgery, an active stomach ulcer, any kind of history of an allergy to any medications, or any of these conditions. 
  • Intake of Nimesulide medicine may result in lightheadedness or slight eyesight impact problems. You should avoid some activities such as operating a machine or driving a car after taking these medicines. 
  • Use and stop taking these medicines after only your doctor’s advice. If in case you notice any kind of side effects you should report to your doctor immediately. 

What if You miss the dose or overdose?

There are no issues or effects, if you miss one or two doses of Nimesulide. The missed dosage has no such adverse impacts or effects unless your doctor does not encourage you to take the dosage before the time for the next dosage. 

Overdrugs are possible by accident. Overdosing or taking more tablets than recommended will keep your body warm. Also, it leads to an emergency medical situation, and contact your doctor or nearest hospital immediately. 

Storage Advice 

  • Nimesulide medicine should be keep at room temperature between 20°C and 25°C and in Fahrenheit 68ºF and 77ºF. 
  • Keep these medicines in a cool place, dry environment, and the original container or cover of the tablets until you want to take them. 
  • Take these medicines away from the Children’s reach and sight. 

Nimesulide and Paracetamol Tablet Uses, Composition, and Side Effects

Nimesulide vs Paracetamol Comparison
NimesulideParacetamole 
Composition It is an aromatic ether compound and composed of two aryl groups: Phenyl and 2-methyl sulfonamide-5-nitrophenyl. It mainly belongs to groups of medicine which hep to relief in pain and reduce fever. 
UsesIt is used during acute pain and menstruation cramps. It is used to relieve pain, fever, headaches, toothaches, and backaches. 
Side effectsDiarrhoeaAcid or sour stomachBlood clotting problemsDizzinessSkin infectionStomach pain and crampsNausea VomitingSwellingTenderness in the upper abdomen

Nimesulide Vs Aceclofenac (composition, uses, side effects)

Nimesulide vs Aceclofenac Comparison,composition, uses, side effects
NimesulideAceclofenac
Composition It is an aromatic ether compound and composed of two aryl groups: Phenyl and 2-methyl sulfonamide-5-nitrophenyl. It is a carboxymethyl ester of diclofenac, aceclofenac is an acid of monocarboxylic. 
UsesIt is used during acute pain and menstruation cramps. It is used for the treatment of ankylosing spondylitis and various kinds of arthritis to relieve pain, inflammation of joints, and swelling. 
Side effectsDiarrhoeaAcid or sour stomachBlood clotting problemsDizzinessSkin infectionStomach pain and crampsAbdominal painLoss of appetiteFlatulenceVomitingSkin rashDiarrhoea

Frequently Asked Questions

Ques. Is Nimesulide an antibiotic?

It is not an antibiotic drug, it is a medicine that belongs to the non-steroidal anti-inflammatory (NSAID) pain-relieving drug. It helps to reduce pain in different situations.

Ques. Can I take Nimesulide with paracetamol?

Paracetamol and Nimesulide lie in the same group of medicines called; pain-relieving drugs. Two medicines of the same group are not advisable to take at the same time. It may increase the potential for gastric ulceration and bleeding in the stomach. Before taking any medicines, you must consult your doctor.

Ques. Does Nimesulide make you drowsy (feeling sleepy)?

If you take these medicines in a prescribed way, it does not make you feel drowsy (feeling sleepy). However, you take it as an overdose, that makes you feel drowsy.

Ques. Does Nimesulide contain sulphur?

No, it does not contain sulphur salt or chemicals.

Ques. Is Nimesulide banned?

Ans. No, it is not ban or has any kind of restrictions according to the Ministry of Health and Family Welfare of India. It is banned for children under 12 years old.

Ques. How quickly does Nimesulide show results?

This medicine shows the impact or effect on your body within 15 minutes and gives relief in pain and inflammation.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Nimesulide tablets, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.