Rabeprazole Sodium and Domperidone Capsules Uses, Side Effects, Doses, and Benefits
Rabeprazole Sodium and Domperidone Capsules are used to treat symptoms of gastrointestinal reflux due to stomach ulcer (Peptic ulcer disease), hyperacidity, and Zolllinger-Ellison syndrome (overproduction of acid due to a pancreatic tumor).
It is also the most effective capsule to treat gastroesophageal reflux disease (GERD) symptoms. It is a medical condition in which the sphincter (valve) at the uppermost organ of the stomach gets hurt or is damaged, irritated, and not working properly due to acid production over the need. This extra production of acid results in juice and acid flowing into the food pipe causing stomach upset, pain, heartburn, and irritation in the stomach.

Rabeprazole Sodium and Domperidone Capsules Uses
Rabeprazole sodium and domperidone capsules are mainly used to treat medical conditions like Gastrointestinal Disorders, stomach pain, acidity, and excessive acid production in the digestive system.
- Treating Acid Reflux and Stomach Ulcers: The most common use of rabeprazole and domperidone is to manage the acid reflux condition in the stomach also called gastroesophageal reflux disease (GERD). It works by decreasing the production of acid and increasing gastric emptying, that combination helps to prevent acid from irritating the esophagus.
Moreover, these capsules are effective in treating stomach and duodenal ulcers. It slows down the rate of acid production and prevents ulcers in the stomach and mouth.

- Alleviating Symptoms of Nausea: Domperidone has the properties of an antiemetic and that combination is used for individuals who suffer from nausea as part of their gastrointestinal disorder. It is also recommended for those patients undergoing treatment that can reduce nausea, including chemotherapy, and gastroparesis medical conditions. In these conditions an empty stomach results in vomiting and discomfort.
- Usage in Pregnancy: The rabeprazole sodium and domperidone capsules used in pregnancy are very sensitive topics and are always taken with careful consideration by the medical practitioner. Normally, this medicine is avoided in pregnancy due to potential risks to the developing fetus. Always consult the doctor before taking this medicine and use it with proper guidance of healthcare during pregnancy.
How Do Rabeprazole Sodium and Domperidone Capsules Work?
Rabeprazole is a proton pump inhibitor (PPI). Its main function is reducing excess acid in the stomach by inhibiting the actions of an enzyme (H+/K+ ATPase). This enzyme lies in the wall of cells that is responsible for gastric acid secretion and damaging tissues in the stomach, food pipe, and duodenum. It results in patients getting relief from acidity and acid problems indigestion, and heartburn.
Domperidone is a D2 receptor antagonist and Prolactin releases and acts on the upper stomach. It accelerates the mobility or movement of the gastrointestinal tract. Also, it reduces the chances of vomiting in the center (chemoreceptor trigger zone-CTZ). Due to this, food easily moves through the pipe and stomach. This medicine is also used sometimes to increase the milk supply in women’s bodies.
Both of the drugs work together and treat the medical conditions of gastrointestinal reflux disease (GERD) and peptic ulcers.
Note: Use Rabeprazole Sodium and Domperidone Capsules only prescribed by the Doctor or medical expert.
Rabeprazole Sodium and Domperidone CapsulesSide Effects
- Nausea or vomiting
- Back pain
- Diarrhea, constipation, stomach pain, flatulence
- Cough, sore throat, runny nose
- Insomnia (difficulty in sleeping)
- Weakness or loss of strength
- Flu-like symptoms
- Dry mouth
- Headache, dizziness
- Benign polyps in the stomach
Precautions for Rabeprazole Sodium and Domperidone Capsules
Here are some important precautions for Rabeprazole Sodium and Domperidone Capsules to treat the above disorders effectively:
- Take it as prescribed by the doctor as per the time and dose.
- Domperidone + Rabeprazole is used for the treatment of acidity and heartburn.
- Take it at least one hour before the meal and most preferably in the morning.
- Inform the doctor if you are facing any other disease or have any other treatment.
- Also tell your health care or doctor if you have a fever, watery diarrhea, or stomach pain.
- If you face any irregularity or irritation after taking this medicine, immediately inform or consult your doctor.
- The use of it for the long term resulted in weak bones and a deficiency of minerals like magnesium.
- Take a proper diet and increase intake of calcium and magnesium or their supplements are recommended by the doctors and your health care advisor.
What if You miss a dose and Overdose Rabeprazole Sodium and Domperidone Capsules?
If you miss one or two doses of this combination may not cause any side effects or create any problems. However, take it as soon as possible with the guidance of the doctor but try to avoid taking two doses together.
In any case, if you take this combination as an overdose, it may cause somnolence, agitation, disorientation, altered consciousness, and extrapyramidal reactions. Immediately tell your doctor about the overdose of medicine and take proper advice.
How to Store Rabeprazole Sodium and Domperidone Capsules?
- Keep Rabeprazole Sodium and Domperidone capsules in a cool and dry place and at the room temperature range of 15°C to 30°C (59°F to 86°F).
- Always keep away from direct sunlight, heat, and moisture.
- Keep containing it in an original package to prevent humidity and air exposure.
- Keep away from the children and avoid any risk of accidental ingestion.
Drug Warnings/ Experts Advice
- Avoid alcohol if you take Domperidone + Rabeprazole capsules.
- A person who is facing gastroesophageal reflux disease should follow the proper diet and lifestyle, incorporating dietary changes according to the GERD-friendly diet. It is a special kind of diet that mainly emphasizes low-acid foods, avoidance of spicy and fatty meals, and reduction of portion sizes.
- Always take this combination before the meal for best results.
Frequently Asked Questions
Ans. Domperidone+Rabeprazole is harmful to those patients who are suffering from hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the drugs. It is also cautiously advised for patients who have kidney or liver disease.
Ans. Yes, Domperidone and Rabeprazole are safe for most of the patients. However, it shows a few side effects in some patients such as stomach pain, diarrhea, dryness in the mouth, flatulence, dizziness, and headache. The most important advice is if you experience any uncommon side effects immediately consult your doctor.
Ans. Yes, Domperidone+Rabeprazole can increase the rate of heartbeat or develop irregular heartbeats (serious arrhythmias). It is considered the most serious side effect of this medicine but the chances of this happening are very low. However, the risk of this happening is higher if you are 60 or older.
Ans. The best time to take Domperidone+Rabeprazole is empty stomach or before your first meal.
Ans. Yes, Rabeprazole and Domperidone can reduce heartburn, gastroesophageal reflux disease (GERD), or peptic ulcer.
Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Rabeprazole Sodium and Domperidone Capsules, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.