Ofloxacin Tablet Uses, Doses, Side Effects, Precautions

Ofloxacin Tablet Uses, Doses, Side Effects, Precautions

Ofloxacin is an antibiotic used to treat a wide variety of bacterial infections in different body parts. It is a fluoroquinolone antibiotic that kills or stops the growth of the bacteria that causes infections. Fluoroquinolone antibiotics are usually prescribed when all other types of treatment for bacterial infections have been exhausted. 

Ofloxacin Tablet Uses

This is a prescription-based medication that a doctor may give to the patient for the treatment of bacterial infections, such as: 

  • Respiratory infections such as pneumonia, bronchitis and sinusitis
  • Urinary tract Infections including bladder and kidney infections
  • Sexually Transmitted Infections such as  Gonorrhea and chlamydia
  • Skin and soft tissue infections such as Cellulitis and abscesses
  • Eye and ear infections in the form of eye and ear drops
  • Digestion or gastrointestinal infections such as Traveller’s diarrhea and typhoid fever
  • Bone or joint infections such as Osteomyelitis

Ofloxacin Tablet Working

Ofloxacin is an antibacterial medication that works against both gram-positive and gram-negative bacteria. The medication works by interfering with bacterial enzymes that are required for bacterial DNA replication. It inhibits bacterial DNA gyrase and topoisomerase IV. Lack of ability to replicate eventually leads to the death of the infection-causing bacteria.

Ofloxacin Tablet Side Effects 

Patients who take Ofloxacin tablets may experience the following common side effects. These side effects are –

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Trouble sleeping or Insomnia

Ofloxacin Tablet Serious Side Effect 

Some of the serious side effects that will require the patient to seek medical attention are as follows – 

  • Tendon Rupture, especially of the Achilles tendon
  • Severe form of diarrhea 
  • Nerve Damage and Seizures 
  • Heart Rhythm problems such as QT prolongation

Ofloxacin Tablets Precautions 

Ofloxacin tablets should be avoided under the following circumstances – 

  • In case a patient has a history of tendon-related disorders
  • Epilepsy or seizure disorders
  • Heart conditions (QT prolong)

In certain scenarios, it should be used only under medical supervision – 

  • Elderly patients as they have a higher risk of tendon rupture
  • Pregnant or breastfeeding women should be prescribed this medication only if necessary
  • This medication may affect the blood sugar levels of diabetics

Ofloxacin Dosage and Strength 

Ofloxacin is available in a variety of strengths such as 200 mg, 400 mg, and 600 mg tablets. The dosage and tablet strength are prescribed on the basis of the infection as well as the severity of the infection. Please note that Ofloxacin tablets can be taken with or without food. However, these tablets should not be taken with dairy products. Dairy products reduce the adsorption of medication into the body, reducing its effect. 

The dosage based on the type of infection is as follows. 

Infection Dosage
UTIs and respiratory infections 200-400 mg twice daily
Gastrointestinal infections400 mg once or twice daily
Sextually Transmitted Disease400 mg as a single dose (for gonorrhea)
Severe Infections Sexually Transmitted Disease

Ofloxacin Drug Interactions 

The Ofloxacin tablets are not recommended for a patient if he/she is taking the following medication: 

  • Antacids or supplements such as calcium, Iron, and Zinc reduce adsorption
  • Blood thinning medication such as Warfarin) as it increases bleeding risks
  • NSAIDs (Ibuprofen, Naproxen) – Higher risk of seizures
  • Drugs affecting heart rhythm – Increased risk of QT prolongation

Ofloxacin Brands In India 

Well-known brands that sell ofloxacin tablets in India are  – 

  • Oflomac
  • Zanocin
  • Oflokem
  • O2 (Ofloxacin + Ornidazole for gut infections)

Ofloxacin Storage Guidelines 

To maintain the effectiveness of ofloxacin tablets they should be stored in the following manner. 

  • They should be stored at a temperature of 20-25 degrees Celsius. Avoid storing them in the freezer or excessively hot places. 
  • They should be stored in a dry place away from humidity. 
  • They should be stored away from direct sunlight as they can degrade due to UV light. 
  • It is best to store the medication in its original packaging.
  • It should be kept away from children and pets 

Ofloxacin Tablets Disposal 

Ofloxacin tablets should be disposed of in a safe manner. These tablets should not be flushed down the toilet and local guidelines with regards to the disposal of the medication should be followed.

Frequently Asked Questions

Ques. What is the antibiotic ofloxacin used for?

Ans. It is used to treat a wide variety of bacterial infections of the gastrointestinal tract, UTIs, skin, soft tissue, and bone infections.

Ques. Is ofloxacin a strong antibiotic?

Ans. Yes, it is a strong antibiotic and should be used with a prescription from a doctor.

Ques. What bacteria does ofloxacin treat?

Ans. Ofloxacin is used to treat a wide variety of both gram-positive and gram-negative infections.

Ques. एंटीबायोटिक ओफ़्लॉक्सासिन किसके लिए प्रयोग किया जाता है?

Ans. शरीर के कई अलग-अलग हिस्सों में कुछ जीवाणु संक्रमणों के इलाज के लिए इस्तिमाल किया जाता है, जैसे फेफड़े की बिमारीअ  (निमोनिया, ब्रोंकाइटिस और साइनोसाइटिस). इसके अलावा यह इन बिमारिओं के लिए भी इस्तेमाल होता है –  

1. यूरिनरी  ट्रैक्ट  इन्फेक्शन्स  जैसे  ब्लैडर  और  किडनी  इन्फेक्शन्स 
2. सेक्सटुअल्ली  ट्रांसमिटेड  इन्फेक्शन्स  जैसे  गोनोरिया  और  चलमीडिए 
3. पैठ की बीमारी जैसे  ट्रैवलर’स  डायरिया  और  टाइफाइड  फीवर 
4. जोड़ो की बीमारी जैसे  ओस्टोमयेलिटिस 

Disclaimer: The information on this blog is strictly for informational purposes. It is not a substitute for professional medical advice. Please consult your doctor before taking any medication.

Glutathione Tablets Doses, Uses, Side Effects, Precautions

Glutathione Tablets: Doses, Uses, Side Effects, Precautions

Glutathione is a naturally occurring antioxidant in the body that plays a crucial role in maintaining overall health. It does this by – 

  • Detoxification
  • Helping maintain skin health 
  • Maintaining skin complexion and tone
  • Supporting the Immune system 
  • Anti-aging and repair in the various cells that are a part of the human body.

The Glutathione tablets are supplements that contain the synthetic version of the Glutathione produced in the body. 

Glutathione Tablets Working

Glutathione works in many different ways. It helps with detoxification because of free radicals. Free radicals are unstable molecules floating around in the human body that can damage the various cells in the body.  Vitamin C and Vitamin E help with this. 

In the liver it binds to the toxins, making it water soluble and easier to eliminate through urine and bile. It helps in the elimination of substances such as heavy metals, pollutants, and harmful chemicals. 

When it comes to skin tone and pigmentation, it reduces melanin production by inhibiting tyrosinase. This medication works more effectively when it is combined with Vitamin C. 

Further, it helps the immune system by enhancing the functioning of white blood cells. It protects these cells from oxidative stress and inflammation. As it promotes healthy cell functioning, it slows down skin aging, wrinkles, and fine lines. 

Glutathione Production In the Human Body

Glutathione is synthesized in the liver, with the help of three key components and these are – 

  1. Glutamate
  2. Cysteine (the most crucial for glutathione production)
  3. Glycine

The conversion of these components to Glutathione is a two-step process. The first step is the combination of  Glutamate and cysteine with the help of glutamate cysteine ligase (GCL). In the next step, Glycine is added by the enzyme glutathione synthetase to form glutathione. 

How To Increase Glutathione Levels Naturally

Glutathione levels can be increased naturally in the body by – 

  • Adding garlic, onions, broccoli, Brussels sprouts, cabbage, and kale.
  • Increasing protein intake
  • Consuming foods rich in vitamin C and healthy nuts
  • Regular exercise 
  • Reducing alcohol and processed food intake

Glutathione Tablet uses

An individual takes Glutathione tablets for a wide variety of reasons. These reasons are as follows, 

  1. Skin whitening and brightening – This compound inhibits melanin production and leads to lighter and even-toned skin. It is often taken with Vitamin C tablets to enhance the effectiveness of Glutathione Tablets.   
  2. Liver health and detoxification – It is used to treat diseases such as fatty liver and hepatitis. 
  3. Healthier skin and Anti-ageing – Helps reduce pigmentation, dark spots, and wrinkles. 
  4. Supporting Immune system, heart, and neurological health – It helps protect against diseases such as Parkinson’s disease. 

Glutathione Tablet Doses

For overall health 250 mg to 500mg can be taken daily. For the purpose of skin whitening 500 mg to 1000 mg is often paired with Vitamin C. Even though this medication is a supplement, you should consult a doctor. 

Glutathione Tablets Adsorption 

The tablets have low bioavailability of Glutathione. This means that the body takes time to absorb this medication. Sometimes liposomal formulations (encasing the medication in fat molecules) are used to make this medication to help improve the adsorption of this medication.

N-acetyl cysteine (NAC) supplements in some cases are a more effective way to add glutathione as they help the body produce glutathione naturally. 

Glutathione Tablet Side Effects 

This medication is generally safe, but some people may experience some side effects. These side effects are as follows – 

  • Skin rashes or allergies
  • Digestive issues (bloating, nausea, or diarrhea)
  • Lowered zinc levels with prolonged use
  • Breathing problems (rare, mostly with IV form)

Reasons For Low Glutathione Levels

Glutathione may decline in the body due to the following natural reasons – 

  • Delicine in levels after 40 years of age due to the body’s natural aging process
  • Lack of a balanced diet
  • Chronic stress
  • Exposure to pollution, alcohol intake, smoking, and heavy metals
  • Certain medical conditions  such as liver disease, diabetes, cancer, neurodegenerative disorders 

How Long Do Glutathione Tablets Take to Work?

  • For skin lightening: 1 to 3 months (visible results vary by skin type and dosage).
  • For detox & general health: Effects may be noticed in a few weeks.
  • Works faster when combined with Vitamin C, a healthy diet, and hydration

Frequently Asked Questions

Ques. When should I avoid taking glutathione?

Ans. Pregnant or breastfeeding women should avoid this medication as the side effects of this medication are not known for pregnant women.

Ques. What are the risks of IV glutathione?

Ans. Some of the risks include – 
Formation of air bubbles in the blood vessels
Sepsis 
Kidney dysfunction
Thyroid dysfunction 
These risks are often due to improper administration of IV or administration of fake glutathione. 

Ques. Can glutathione be used to treat Parkinson’s disease? 

Ans. Glutathione can’t be used to treat Parkinson’s disease, as its risks and benefits have not been assessed for the treatment of Parkinson’s disease. 

Disclaimer: The information on this blog is strictly for informational purposes. It is not a substitute for professional medical advice. Please consult your doctor before taking any medication.

Budecort Doses, Symptoms, Uses, Precautions, Side Effects

Budecort: Doses, Symptoms, Uses, Precautions, Side Effects

Budesonide medication has the brand name Budecort. The medication is a corticosteroid (steroid-based medication) that is primarily used for the treatment and management of Asthma and other respiratory-related conditions. It helps make breathing easier by reducing inflammation in the airways. 

Budecort Uses

The uses of Budecort are as follows, 

In some cases, inflammatory bowel disease.

  • Asthma management, 
  • Allergic Rhinitis, 
  • Chronic Obstructive Pulmonary Disease or COPD and 
  • This medication is available as an inhaler, respules, nasal spray, and tablets. 

Asthma Management 

It helps manage symptoms such as wheezing and shortness of breath by helping reduce the inflammation in the airways.

COPD and Allergic Rhinitis 

It is used in the severe cases of Chronic Obtrusive Pulmonary Disease to help reduce inflammation in the airways.   In the form of a nasal spray, it is used to relieve symptoms of nasal congestion and sneezing. 

Inflammatory Bowel Diseases 

Budecort is used in some cases of Inflammatory Bowel Diseases as well. Some inflammatory diseases such as Crohn’s disease and Ulcerative Colitis. Budecort tablets are mostly used to treat inflammatory bowel diseases. 

Budecort Working 

The Budecort is a medication that contains Budesonide compound, Budesonide is a steroid and it works in three ways. It works by 

  • Decreasing inflammation in the airways 
  • Helping in preventing Asthma attacks
  • Reducing the production of mucous in the airways

How To Take (administration) Budecort and Its Doses   

Budecort is available in four different forms, inhaler, respules, oral tablets, and nasal spray. 

  • An Inhaler typically contains 100 mcg or 200 mcg concentration per puff and it can be taken twice daily. 
  • Budecort respules will require a nebuliser. The recommended dosage for respules is 0.5mg to 1mg per day. 
  • The dosage of Budecort tablets depends upon the condition the patient is suffering from as well as the doctor’s recommendation. 
  • Budecort nasal spray can be used once or twice daily and one or two sprays can be done in each nostril.   

Budecort Side Effects 

The use of Budecort has some common side effects. The patient may experience – 

  • Sore throat, cough
  •  Week, scary or husky voice
  • Dizziness, headache 
  • Stomach pain 
  • Nausea 
  • Dryness in mouth or throat

Budecort – Serious and Rare Side Effects  

In some cases patients taking Budecort can experience some serious and rare side effects are – 

  • Increased risk of infection 
  • Long-term use can lead to adrenal suppression
  • Prolong use can also lead to osteoarthritis

Budecort Precautions 

This medication is not for emergency use or sudden asthma attacks. Further, this medication can increase the chances of oral thrush (bacterial infection of the mouth). Oral thrush can be prevented by regularly rinsing the mouth. 

This medication is not suitable for the following group of people – 

  • Patients with untreated infections 
  • People with severe liver disease
  • People with tuberculosis
  • It may not be suitable for pregnant or breastfeeding women  

Budecort Interactions With Other Medications

This medication can interact with other corticosteroids, leading to more side effects. Further, it should not be combined with strong CYP3A4 inhibitors such as ketoconazole, and ritonavir. 

Budecort Storage 

Budecort should be stored in a cool dry place away from direct sunlight. Incase inhalers and respules in a sealed packet to avoid cross-contamination. For inhalers, do not puncture them. 

Frequently Asked Questions

Ques. Can Budecort be used during an Asthma attack?

Ans. No, this medication is not for emergency use and can’t be used during an asthma attack.

Ques. How long does Budecort take to take effect?

Ans. Depending upon the condition it can take from a few days to a few weeks.  

Ques. Can Budecort be used by children?

Ans. In rare circumstances a doctor may prescribe low-dose Budecort inhalers or respules for nebulisation for children.

Ques. Does Budecort cause weight gain?

Ans. Long-term use can cause weight gain.

Disodium Hydrogen Citrate Syrup Uses, Doses, Precautions and Side Effects

Disodium Hydrogen Citrate Syrup Uses, Doses, Precautions and Side Effects

Disodium Hydrogen Citrate Syrup is a commonly used urinary alkalizer. It is used to help neutralize excess uric which helps reduce urine acidity. Doctors give this medication to patients for conditions like urinary tract infections (UTIs), kidney stones, and gout.  

This medication is sold under the following common brand names:  

  • Cital  
  • Alkacitral
  • Citralka
  • Alkasol 

Disodium Hydrogen Citrate Syrup Uses

This syrup is used to treat a wide variety of diseases such as certain metabolic conditions, UTIs, Kidney stones, and Gout. These conditions often result from the production and presence of excess acid in the body.

Disodium Hydrogen Citrate Syrup Working

Disodium Hydrogen Citrate works by neutralizing the amount of uric acid in the body. It is an alkalizer that increases the PH in urine. This helps in the removal of excess uric acid. A decreased amount of uric acid helps in the prevention of Gout and the prevention of certain types of kidney stones, thereby preventing gout and certain types of kidney stones. 

Disodium Hydrogen Citrate takes a few minutes to start working and its effect lasts for around four to six hours.

Disodium Hydrogen Citrate Syrup Doses and Administration  

This medication should be taken only after it has been diluted with water. It can’t be taken directly in its concentrated form. The usual recommendation is to mix 1-2 teaspoons (5-10 ml) in a glass of water. The patient should take it 2-3 times daily or as prescribed. It is best taken after meals. While these are some generic guidelines, it is necessary to follow the specific dosage prescribed by your doctor. Further, 

  • An overdose can lead to side effects. 
  • It should be taken along with meals and a full glass of water in order to prevent an upset stomach. 
  • Take it as suggested by the doctor to get the maximum benefits from this medication. 
  • With this medication, you might experience some stomach pain. Consult your doctor if the stomach pain becomes too much to tolerate. 

Disodium Hydrogen Citrate Syrup Side Effects

Some of the common side effects that a patient may experience the following side effects:

  • Nausea or vomiting  
  • Abdominal discomfort  
  • Loose stools or diarrhea  
  • Increased thirst 
  • Tiredness
  • Stomach cramps
  • Flatulence
  • Diuresis

Disodium Hydrogen Citrate Syrup Storage

Store this medication in a cool dry place and away from the reach of children.

Disodium Hydrogen Citrate Syrup Precautions

One of the things to keep in mind while taking this medication is that it is important to stay hydrated while taking this medication. Further, this medication should not be taken with antacids unless prescribed by a doctor. 

Further, this medication may not be suitable for you if you have pre-existing conditions such as kidney disease, hypertension, or heart problems. 

Frequently Asked Questions

Ques. Can Disodium Hydrogen Citrate be used for cough?

Ans. No. This medication is not used for the treatment of cough. It is an alkaliser and is primarily used as a neutralizer for the excess acid produced in the body.

Ques. Can I take disodium hydrogen citrate syrup?

Ans. Yes, If it has been prescribed by the doctor.

Ques. How to use disodium hydrogen citrate?

Ans. Mix 1-2 teaspoons (5-10 ml) in a glass of water and drink it after meals.

Ques. How to use disodium hydrogen citrate syrup for urine infection?

Ans. The recommended approach is to mix 1-2 teaspoons (5-10 ml) in a glass of water and drink it after meals. However, it is best to follow your doctor’s advice on this.

Disclaimer: The information on this blog is strictly for informational purposes. It is not a substitute for professional medical advice. Please consult your doctor before taking any medication.

Itraconazole Capsules 200 mg Uses, Doses, Precautions, Side Effects

Itraconazole Capsules 200 mg: Uses, Doses, Precautions, and Side Effects

Itraconazole capsules are used to treat patients who have serious fungal or yeast infections. This is a prescription medication and can’t be bought without a prescription. The medication is sold both as a capsule and a solution. This medication may not be suitable for everyone. Tell your doctor about any allergies you may have before taking this medication.

Itraconazole Uses 

It treats yeast and fungal infections. It is a prescription medication that may not be suitable for everyone. Itraconazole is a broad-spectrum medication and is approved for use in the following diseases: 

  • Blastomycosis, 
  • Sporotrichosis, 
  • Histoplasmosis, 
  • Onychomycosis

This medication is not suitable for the use of treatment of infections that affect the central nervous system.

Itraconazole Capsules Doses

This medication’s doses and effects can vary from brand to brand. It is important to get the medication from the brand that your doctor has prescribed. Below is the recommended dosage from the most widely used Itraconazole Capsules. 

Further, the dose will depend on every individual case. The amount of medication will depend upon the strength of the medication. If your dosage is different from the one in the table, don’t change it according to the table. The dosage given here are generic guidelines about the medication. Follow your doctor’s advice about this medication.

Infection Medication Brand Dosage Adult/Children
AspergillosisSporanox®200 to 400 milligrams (mg) per dayAdult (The dosage needs to be determined by the doctor in the case of children)
Tolsura™130 mg (two capsules) once or 2 times a dayAdult (The dosage needs to be determined by the doctor in the case of children)
Blastomycosis or HistoplasmosisSporanox®200 milligrams (mg) (two capsules) once a dayAdult (The dosage needs to be determined by the doctor in the case of children)
Tolsura™130 mg (two capsules) once a dayAdult (The dosage needs to be determined by the doctor in the case of children)

Itraconazole Missed Dose 

It would be best to call your doctor or pharmacist if you miss a dose.

What are Itraconazole Side Effects?

Itraconazole is a strong medication and is known to have the following side effects:

  • Diarrhea
  • Dizziness
  • Itching
  • Liver damage
  • Headache
  • Nausea
  • Stomach pain
  • Fever
  • Impotence
  • Loss of appetite
  • Tiredness
  • An unpleasant aftertaste
  • Double vision
  • Irregular breathing
  • Hair loss
  • Menstrual changes
  • Swelling
  • Constipation
  • Cracks in the skin
  • Decreased libido
  • Depression
  • Hearing loss
  • Arthralgia
  • Nausea, vomiting, diarrhea and constipation

Itraconazole Capsules Interactions

It is strongly recommended that you discuss all the medications that you are taking with your healthcare provider when the doctor prescribes Itraconazole. Do not take this medication if you are taking any of the following medications. These medications are – 

  • Dihydroergotamine
  • Disopyramide
  • Dofetilide
  • Dronedarone
  • Eletriptan
  • Eliglustat
  • Eplerenone
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Felodipine
  • Fesoterodine
  • Finerenone
  • Flibanserin
  • Fluconazole
  • Gepirone
  • Irinotecan
  • Irinotecan Liposome
  • Isavuconazonium Sulfate
  • Ivabradine
  • Ketoconazole
  • Levoketoconazole
  • Lisuride
  • Lomitapide
  • Lonafarnib
  • Lovastatin
  • Lurasidone
  • Mavacamten
  • Mesoridazine
  • Metergoline
  • Alfuzosin
  • Alprazolam
  • Astemizole
  • Atazanavir
  • Avanafil
  • Bepridil
  • Bromocriptine
  • Cisapride
  • Colchicine
  • Conivaptan

Further, this medication may not be suitable for you if you have the following medical conditions. Some of these conditions are – 

  • Chronic obstructive pulmonary disease (COPD) 
  • Edema (body swelling or fluid retention) 
  • Heart attack or any kind of heart disease
  • Elevated liver enzymes 
  • Kidney disease 

This medication can make this condition worse.

This medication should not be taken along with alcohol or tobacco. Further, this medication may interact with certain foods and drinks as well. Discuss with your doctor before taking this medication.

Itraconazole Storage

The medication should be stored in a cool dry place and away from direct sunlight. Do not freeze the medication. Keep it out of the reach of children.

Itraconazole Precautions 

There are a few important precautions that need to be kept in mind before starting on this medication. Some of these things are as follows: 

  • Read the patient information on the leaflet and ask your doctor if you have any questions.
  • Stick to the duration and the dosage prescribed by the doctor. Take the medication at the same time each day. 
  • This medication can hurt pregnant women or women planning on getting pregnant. Make sure that your doctor knows about this before starting treatment with this medication. 
  • Inform your doctor in case you become pregnant while taking this medication. 
  • Contact your doctor if you are feeling any chest pain, tightness, decreased urine output, dilated neck veins, extreme fatigue, irregular breathing, an irregular heartbeat, swelling of the face, fingers, feet, or lower legs, trouble breathing, or weight gain. You need to visit your doctor as soon as possible with these symptoms as they are symptoms of congestive heart failure.
  • In rare cases, it can also cause liver problems, nerve problems, or issues with hearing. 
  • Do not drive after taking this medication. 
  • Do not take any additional medication before discussing it with your doctor.

Frequently Asked Questions

Ques. Is itraconazole for dandruff?

Ans. People sometimes use it to treat skin infections, including dandruff.

Ques. Is itraconazole for ringworm?

Ans. Yes, it is sometimes prescribed for the treatment of ringworms in adults and not children or senior citizens. 

Ques. Is itraconazole used for dogs?

Ans. Yes, it is used sometimes for off-label use to treat fungal infections in dogs. 

Ques. Can itraconazole cause hair loss?

Ans. Yes, it can cause hair loss in rare cases.

Disclaimer: The information on this blog is strictly for informational purposes. It is not a substitute for professional medical advice. Please consult your doctor before taking any medication.

Etoricoxib Tablets IP 90 Mg Uses, Doses, Side Effects, Benefits, and Prescriptions

Etoricoxib Tablets IP 90 Mg :Uses, Doses, Side Effects, Benefits, and Prescriptions

Etoricoxib tablets IP 90 mg are a non-steroidal anti-inflammatory medication (NSAID) that helps to reduce pain in various medical conditions in the body. In this blog, we will give more information about the same medicine that is toricoxib tablets IP 90 mg including uses, side effects, doses, benefits, and many more important details.

What is an Etoricoxib Tablet?

Etoricoxib is a drug that belongs to non-steroidal anti-inflammatory medication (NSAID) and the COX-2 inhibitor group of medicines. In comparison with other medicines of the same group of NSAIDs, Etoricoxib is the most effective medicine.

Etoricoxib Tablets IP 90 Mg chemical compound

It helps to reduce pain, inflammation, and swelling in illnesses including ankylosing spondylitis, osteoarthritis, gout, rheumatoid arthritis, and persistent low back pain. This medicine is also prescribed for patients who have minor pain in dental surgery.

Clinical data
AHFS/Drugs.comInternational Drug Names
Pregnancy categoryAU: CNot recommended
Routes ofadministrationBy mouth
ATC codeM01AH05 (WHO)
Legal status
Legal statusAU: S4 (Prescription only)BR: Class C1 (Other controlled substances)UK: POM (Prescription only)
Pharmacokinetic data
Bioavailability100%
Protein binding92%
MetabolismLiver, CYP extensively involved (mainly CYP3A4)
Elimination half-life22 hours
ExcretionKidney (70%) and fecal (20%)
Chemical and physical data
FormulaC18H15ClN2O2S
Molar mass358.84 g·mol−1

It is sold under the brand name Arcoxia and is a selective COX-2 inhibitor developed and commercialized by Merck. This medicine is approved in 63 countries across the world as of 2007, except the USA where the Food and Drug Administration sent a Non Approval Letter to Merck and asked to provide more data on the medicine. The medicine was patented in 1996 and approved for medical use in 2002.

Important Note: Before using Etoricoxib medicine, you must consult a doctor or health care expert.

Etoricoxib Tablet Uses

Etoricoxib Tablet Uses

The medicine is used in several pain conditions. Some of the common medical conditions in which this medicine is used:

  • Gout
  • Osteoarthritis
  • Rheumatoid arthritis
  • Chronic low back pain
  • Ankylosing spondylitis
  • Acute and chronic musculoskeletal pain

How Does Etoricoxib Tablet Work?

Etoricoxib is an NSAID drug known as a COX-2 inhibitor. It works by blocking the release of certain enzymes that are responsible for inflammation and pain in the body. By reducing prostaglandin levels, Etoricoxib helps alleviate pain and inflammation.

Etoricoxib Tablet Side Effects 

Some of the common and major side effects of Etoricoxib are:

  • Stomach pain
  • Dry socket (severe pain after tooth extraction)
  • Swelling of the legs or feet due to fluid retention
  • Dizziness
  • Gastritis (inflammation of the lining of the stomach)
  • Headache
  • Increased blood pressure
  • Wheezing or shortness of breath
  • Palpitations (pounding heart)
  • Constipation
  • Flatulence
  • Mouth ulcers
  • Heartburn
  • Diarrhea
  • Indigestion (dyspepsia)
  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Inflammation of the esophagus (food pipe)
  • Flu-like illness (fever, cold, cough, or sore throat)
  • Changes in blood tests related to your liver
  • Weakness
  • Fatigue (tiredness)

Note: If you face any serious side effects, immediately consult your doctor or healthcare expert for treatment. Don’t ignore or take it easy on these serious side effects that may cause serious medical conditions in your body.

What Precautions Should be Taken for the Etoricoxib Tablets? 

  • When compared to other NSAIDs like Ibuprofen or Naproxen, it might result in fewer stomach issues.
  • It could make you feel exhausted and lightheaded. Until you understand how it affects you, avoid driving and other activities that require focus.
  • Alcohol may produce significant sleepiness, so avoid drinking it while taking this medication.
  • While taking this medication, keep a close eye on your blood pressure, especially during the first two weeks of treatment.
  • If you have a history of liver or renal illness, high blood pressure, heart disease, or stomach ulcers, let your doctor know.
  • To keep an eye on your liver function throughout long-term treatment, your doctor might wish to perform routine blood tests.
  • Do not take Etoricoxib if you are pregnant, planning to conceive, or breastfeeding.

How to Use Etoricoxib Tablets?

Take etoricoxib tablets once daily, you can take it with or without food.

Dosage may change based on the condition being treated:

  • Osteoarthritis: 30 mg tablet daily, may increase to 60 mg if needed.
  • Pain after dental surgery: 90 mg tablet daily for three days.
  • Acute gout: 120 mg tablet daily for up to eight days.
  • Rheumatoid arthritis and ankylosing spondylitis: 60 mg tablet daily, may increase to 90 mg if necessary.

Note: Always take the dosage prescribed by the doctor.

What if You Miss a Dose?

  • If by chance you miss a dose, take it as soon as possible before the time of the next dose. Give at least a 4-5 hours gap between the two doses, if you are near to the next dose time then don’t take your first dose and take the next dose on time. 
  • If you take the medicine as an overdose by accident and experience extreme side effects or symptoms that may include nausea, vomiting, diarrhea, Fluttering heartbeat, Frequent urination, sweating, Breathing or swallowing trouble, etc., immediately consult your doctor.
  • Do not take double or twice doses together, no doctor or any medical expert is recommended in this condition. 

Where should You keep Your Medication?

  • Store the Etoricoxib at a normal room temperature between 20ºC and 25ºC (68ºF and 77ºF).
  • Do not place the medicine under direct sunlight, heat, and moisture. 
  • Always keep the tablets in an original package to store them well. 
  • Do not keep the tablets in the freezer or an extremely cold place. 
  • Keep it out of reach of children and store it safely where kids can’t reach.

Comparison of an Etoricoxib Medicine with a Naproxen

EtoricoxibNaproxen
CompositionEtoricoxib is the active ingredient in this medication. Etoricoxib comes as film-coated tablets in 30, 60, 90, or 120 mg doses.At a pH of 7, Naproxen sodium is a freely soluble, crystalline solid ranging in color from white to creamy white.
UsesIn arthritic conditions such as osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, Etoricoxib reduces inflammation and relieves pain.Naproxen is a nonsteroidal anti-inflammatory medication (NSAID). It alleviates joint and muscular pain and swelling (inflammation).
Side Effects
Feeling worn out,
High blood pressure,
Diarrhea or constipation,
Fatigue,
Stomach pain,
Difficulty breathing		Changes in vision, Skin Rash, Severe indigestion, Frequent sore throat, Feeling sleepy and tired

Warning for Etoricoxib Tablets?

  • Pregnant women should use etoricoxib only if necessary after consulting a doctor.
  • Breastfeeding women must inform the doctor before using etoricoxib due to potential risks to the infant.

Frequently Asked Questions

Ques. How long do I need to take Etoricoxib?

Ans. You need to take it as per the recommendation of the doctor and also follow the doses prescribed by the healthcare expert.

Ques. Does Etoricoxib cause sleepiness?

Ans. In some cases, it may cause sleepiness, a feeling of spinning (vertigo), and dizziness. If you are experiencing any of these symptoms then try to avoid driving or operating machines and any focused activities.

Ques. Can Etoricoxib be taken with food?

Ans. Yes, you can take it with or without food. If you take it with food it may help reduce the risk of gastrointestinal side effects.

Ques. Is etoricoxib safe for kidneys?

Ans. Yes, it is normally considered safer for kidney function compared to COX-1 inhibitors like naproxen and ibuprofen. However, individual factors and medical history should be considered.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Etoricoxib Tablets, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Cefixime Tablet Uses, Side Effects, Benefits, and Precautions

Cefixime Tablet Uses, Side Effects, Benefits, and Precautions

Various drugs are used to treat different infections in the body. Cefixime is one of the drugs used to treat bacterial infections in the body. In this blog, you will get all the information about the Cefixime tablet including uses, dosage, benefits, side effects, and many more. 

About Cefixime Tablet

Cefixime is an antibiotic medicine that is used to treat several bacterial infections in the body. It is sold under the brand name Suprax among others. It counters infections caused by bacteria like Gonorrhea (a sexually transmitted disease),  Bronchitis (infection of the airway tubes leading to the lungs), and infections of the ears, throat, tonsils, and urinary tract. The medicine is in a class of medications known as Cephalosporin antibiotics. 

Cefixime Tablet Chemical Compound Structure
Clinical data
Trade namesSuprax, others
AHFS/Drugs.comMonograph
MedlinePlusa690007
License dataUS DailyMed: Cefixime
Routes ofadministrationBy mouth
Chemical and physical data
FormulaC16H15N5O7S2
Weight Average: 453.45Monoisotopic: 453.041289239
TypeSmall Molecule
Molar mass453.44 g·mol−1
3D model (JSmol)Interactive image

It is an antibiotic drug that will not work for cold, flu, or other viral or fungal infections. It treats various bacterial infections such as otitis media, pneumonia, gonorrhea, strep throat, urinary tract infections, and Lyme disease. 

Cefixime was patented in 1979 but approved for medical use in the United States in 1989. It is also mentioned in the list of essential medicines by the World Healthcare Organization’s List of Essential Medicines. Also, it is available as a generic medication in the USA. 

Unnecessary use of this medicine may increase the risk of getting an infection later that resists antibiotic treatment. The medicine is taken by mouth. 

Important Note: Before using Cefixime medicine, you must consult a doctor or health care expert.

Cefixime Tablet Uses

Cefixime Tablet Uses

Cefixime is used to treat sinus or bacterial infections in penicillin-allergic patients and many more including:

  • Pneumonia
  • Shigella (an infection that causes severe diarrhea)
  • Salmonella (an infection that causes severe diarrhea)
  • Typhoid fever (a serious infection that is common in developing countries)

How Does Cefixime Tablet Work?

Cefixime is an antibiotic that kills the bacteria which cause bacterial infection in the body. It works to protect the body from forming the bacterial protective covering (cell wall) that is essential for them to survive in the body. 

Side Effects of Cefixime Tablet

Cefixime may cause some common side effects that your doctor tells you while taking this medicine. Some common side effects are mentioned below:

  • Stomach pain
  • Diarrhea
  • Vomiting
  • Gas
  • Heartburn
  • Nausea

Here are some uncommon side effects that are serious. If you experience these serious side effects contact your doctor and tell them about medical conditions. Those serious side effects are:

  • Rash
  • Itching
  • Watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment
  • A return of sore throat, fever, chills, or other signs of infection
  • Hives
  • Swelling of the face, throat, tongue, lips, and eyes
  • Difficulty breathing or swallowing
  • Wheezing

Note: If you face any serious side effects, immediately consult your doctor or healthcare expert for treatment. Don’t ignore or take it easy on these serious side effects that may cause serious medical conditions in your body. 

What Precautions Should be Taken?

  • Don’t take Cefixime, if you are allergic to cephalosporin antibiotics including cefadroxil cefazolin (Ancef, Kefzol), cefepime (Maxipime), cefaclor (Ceclor), cefditoren (Spectracef), cefdinir, cefprozil, cefoxitin (Mefoxin), cefotaxime (Claforan), ceftaroline (Teflaro), cefpodoxime,  cefotetan, cefuroxime (Zinacef), cefoxitin (Mefoxin), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax), ceftriaxone (Rocephin), or cephalexin (Keflex); penicillin antibiotics, or any other medications.
  • Tell your doctor what prescription and nonprescription medications, nutritional supplements, vitamins, and herbal products you are taking. So that your doctor changes or limits doses of the medicines or monitors carefully your side effects. 
  • Cefixime may decrease the effectiveness of hormonal contraceptives or birth pills, rings, injections, and patches). You may use another way to counter the pregnancy while taking cefixime. 
  • Tell or ask your doctor about another way of preventing pregnancy and birth control. 
  • Also tell your doctor if you have gastrointestinal problems, especially colitis or kidney or liver disease. 
  • Tell your doctor if you are pregnant or breastfeeding women. Cefixime may be harmful to your child. 

What if You Miss a Dose?

  • If by chance you miss a dose, take it as soon as possible before the time of the next dose. Give at least a 4-5 hours gap between the two doses, if you are near to the next dose time then don’t take your first dose and take the next dose on time. 
  • If you take the medicine as an overdose by accident and experience extreme side effects or symptoms that may include nausea, vomiting, diarrhea, Fluttering heartbeat, rash or itching, sweating, Breathing or swallowing trouble, etc., immediately consult your doctor.
  • Do not take double or twice doses together, no doctor or any medical expert is recommended in this condition. 

How should You keep Your medication?

  • Store the Cefixime tablets at a room temperature of 20°C and 25°C (68°F and 77°F).
  • Do not place the medicine under direct sunlight, heat, and moisture. 
  • Always keep the tablets in an original package to store them well. 
  • Do not keep the tablets in the freezer or an extremely cold place. 
  • Keep it out of reach of children and store it safely where kids can’t reach. 

Drug Warnings or Expert Advice

Don’t take Cefixime tablets, if you are allergic to cefixime’s salts such as Cefzil, Omnicef, Ceftin, Keflex, and others. Before taking the medicine, tell your doctor about your allergy to penicillin.

Comparison of Cefixime with Amoxicillin

CefiximeAmoxicillin
CompositionInactive ingredients contained in Cefixime are dibasic calcium phosphate, lactose monohydrate, magnesium stearate, pregelatinized starch, and titanium dioxide.It is an amino-penicillin, which is made by adding an additional amino group to penicillin.
UsesSeveral bacterial illnesses, including bronchitis, gonorrhea, ears, throat, tonsils, and urinary tract infections, are treated with Cefixime.It mainly treats bacterial infections such as tooth abscesses and chest infections (including pneumonia).
Side EffectsUpset StomachNausea and vomiting loss of appetiteVaginal itching or discharge increased urination during the nightMild HeadacheFeeling hot or coldie or tightness in the chestDizzinessSpinning feeling

Frequently Asked Questions

Ques. How long should I take Cefixime?

Ans. It is normally recommended for 7-14 days by the doctors. Take it to complete your course that is prescribed by the doctor.

Ques.  Is Cefixime safe for the kidneys?

Ans. Yes, it is safe for the kidneys when taken as saline medicine but when taken with aminoglycosides or other cephalosporins antibiotics, it may cause kidney damage. Take the medicine prescribed by your doctor.

Ques. Which bacteria is killed by cefixime?

Ans. Cefixime is effective against various bacteria, including Haemophilus influenzae, Streptococcus pneumoniae, Neisseria gonorrhoeae, and Escherichia coli, among others.

Ques. Is cefixime good for UTI?

Ans. Yes, cefixime is commonly used to treat urinary tract infections (UTIs) caused by susceptible bacteria.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Cefixime tablets, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Aceclofenac Tablet Uses, Benefits, Side Effects, and Precautions

Aceclofenac Tablet: Uses, Benefits, Side Effects, and Precautions

Aceclofenac tablets are commonly for the treatment of Fever, Headache, Pain relief, Dental pain, and Postoperative pain. It is for both long-term and short-term use. It is a non-steroidal anti-inflammatory medication (NSAID) Category of drugs. Patients can also take it for muscle pain and post-surgical pain.

Aceclofenac Tablet Uses

Aceclofenac Tablet Uses

This tablet is for the treatment of various pain and inflammation-related conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal pain, post-operative pain, gout, and ankylosing spondylitis. 

Osteoarthritis

It helps improve the quality of life and mobility of osteoarthritis patients by reducing joint pain, stiffness, and swelling.

Rheumatoid arthritis

In this case, it helps in managing autoimmune damage to the joints and provides relief from pain, inflammation, and swelling. 

Ankylosing spondylitis

One of the main symptoms of this disease is inflammation of the spine. The symptoms are chronic back pain and stiffness chronic back pain and stiffness. 

Gout

Excess uric acid in the joints causes Gout. Aceclofenac helps reduce the pain and inflammation caused due to this.

Patients can also take it for the treatment of sprains and other similar types of muscle. Doctors give these tablets to patients as a part of their post-operative care as well. Menstrual cramps and pain can also be treated with Aceclofenac tablets.

Aceclofenac Working 

Aceclofenac blocks the production of prostaglandins. Prostaglandins are the chemicals in the body that are responsible for pain and inflammation.

Aceclofenac Tablet and doses

A patient can take a 100mg tablet twice daily, once in the morning and once in the evening. It should be taken after meals and should not be crushed. Swallow the whole tablet with a glass of water. 

Aceclofenac Tablet Side Effects

This medication is generally well tolerated by the body. However, it does have some common side effects. These side effects are – 

  • Nausea and vomiting
  • Indigestion and stomach pain
  • Diarrhea or constipation
  • Dizziness and headache

Aceclofenac Tablet Severe Side Effects

Some of the rare but severe side effects include the following – 

  • Gastric ulcers and bleeding
  • Liver or kidney problems
  • Severe allergic reactions (rash, swelling, difficulty breathing)
  • Increased blood pressure and heart issues

Aceclofenac Tablet Precautions

The following types of patients should avoid taking Aceclofenac tablets – 

  • Pregnant or breastfeeding women (unless prescribed by a doctor)
  • Patients with stomach ulcers or gastrointestinal bleeding
  • People with kidney or liver disease
  • Patients with heart disease or high blood pressure
  • Individuals allergic to NSAIDs like ibuprofen or aspirin

Drug Interactions

Aceclofenac can interact with the following medications and can reduce their effectiveness and possibly increase their side effects –  

  • Blood thinners (warfarin, aspirin)
  • Other NSAIDs (ibuprofen, diclofenac)
  • Diuretics & antihypertensive drugs 
  • Methotrexate & corticosteroids

Alternatives 

Some of the alternative medicines in this area – 

  • Diclofenac
  • Ibuprofen
  • Naproxen
  • Paracetamol (for mild pain) 

Comparison of Aceclofenac vs. Aceclofenac + Paracetamol Tablets

Aceclofenac vs. Aceclofenac + Paracetamol Tablets Both medications are known for the treatment of pain and inflammation, but they differ in effectiveness, working, and safety.

Feature Aceclofenac TabletNSAID (Non-Steroidal Anti-Inflammatory Drug) inhibits the COX-2 enzyme, reducing inflammation and pain.
CompositionAceclofenac (100 mg)Aceclofenac (100 mg) + Paracetamol (325/500 mg)
Mechanism Of ActionNSAID (Non-Steroidal Anti-Inflammatory Drug) inhibits COX-2 enzyme, reducing inflammation and pain.Aceclofenac reduces inflammation, while Paracetamol enhances pain relief and has an antipyretic effect.

How To Choose Between The Two?

Aceclofenac alone is preferable for long-term use due to a lower risk of liver damage. Aceclofenac + Paracetamol has stronger pain relief and antipyretic action but is more suitable for short-term use. 

Note: Always consult a doctor before using either medication, especially for prolonged use.

Aceclofenac Tablet Brands

Brand NameManufacturerDosage Form Price IN INR
HifenacIntas Pharmaceuticals LtdTablet₹62.50 for 10 tablets
ZerodolIpca Laboratories Ltd.Tablet₹25.00 for 10 tablets 
DolowinMicro Labs Ltd. Tablet₹30.00 for 10 tablets
MovonIpca Laboratories Ltd.Tablet₹28.00 for 10 tablets 

Frequently Asked Questions

Ques. How long can I take Aceclofenac safely?

Ans. Yes, it is safe for long-term use and can be taken twice daily. However, it is necessary to follow the dosage and duration recommended by the doctor.

Ques. Is Aceclofenac safe for long-term use?

Ans. Yes, it is safe and can be taken for long-term use and can be taken for a week. However, it should be monitored by the doctor.

Ques. What happens if I miss a dose?

Ans. Take it as soon as you remember it, however, don’t take it close to the next dose.

Ques. Can Aceclofenac be taken daily?

Ans. Yes, it can be taken twice daily, however, it is necessary to follow the dosage and duration recommended by the doctor.

Ques. Can I take Aceclofenac without food?

Ans. No, it should not be taken on an empty stomach.

Ques. Is Aceclofenac better than Diclofenac or Ibuprofen?

Ans. Aceclofenac is considered to be as effective as Diclofenac for pain relief. However, Aceclofenac has fewer side effects.

Disclaimer: We are not any professional experts in the medical field and we write all the information after researching on the internet. The motive of this blog is to provide information about this medicine. Before taking any action regarding the use of Aceclofenac Tablet Uses, please consult and seek guidance from a qualified doctor. Do not rely solely on the information provided here.

Vonoprazan Tablet Uses, Doses, Side Effects and Precautions

Vonoprazan Tablet Uses, Doses, Side Effects and Precautions

Vonoprazan is a new medication that entered the Indian Market in 2024. Its chemical formula is C17H16FN3O2S. Vonoprazan is a medication that is classified as a potassium-competitive acid blocker (PCAB) and is used to manage various acid-related gastrointestinal conditions. This medication is an alternative to medicines that use the proton pump inhibition model (PPI). PPIs can not be used to treat acid-related issues for patients who have the following conditions: 

  •  Patients with a history of heart conditions (e.g., prolonged QT interval).  
  •  Those with gastrointestinal bleeding or bowel perforation.  
  •   Breastfeeding women (domperidone may pass into breast milk).  

Vonoprazan 20mg Tablet Uses

Vonoprazan Tablet Uses

Vonoprazan has primarily been used for the treatment of acid-related issues in the stomach. These acid-related issues include the following: 

  • Reducing associated heartburn symptoms.
  • Treatment of non-erosive gastroesophageal reflux disease (GERD).
  • Treatment of Helicobacter pylori (H. pylori) infection when combined with antibiotics such as amoxicillin and clarithromycin. 

Vonoprazan Tablet Working

Its mechanism is different from other medications that use proton pump inhibitors (PPIs) mechanism. It works by inhibiting gastric acid secretion by competitively blocking potassium ions on the proton pump in stomach lining cells. 

Vonoprazan represents a significant advancement as well as an effective and efficient alternative to medications that are proton Pump Inhibitors (PPIs). 

This medication works by being a potassium-competitive acid blocker (PCAB). It competes with the potassium ions to bind to the proton pump, effectively blocking its function. This reduces the hydrogen ion secretion which helps reduce overall gastric acid production. Due to this mechanism, it remains effective for a long time. 

Vonoprazan Dosage and Administration

Vonoprazan is available in capsule form and can be taken with or without food. The dosage depends upon the condition it is prescribed for, and one should follow the doctor’s advice. For erosive esophagitis, the recommended dosage is once daily for up to 8 weeks. Depending upon the doctor it can be prescribed for a longer period. It is also used in combination with other medications as well. In the case of H. pylori eradication, the patient takes it twice daily with antibiotics for 14 days.

Vonoprazan Tablet Side Effects

Some of the common side effects that a patient may experience are – 

  • Constipation, 
  • Diarrhea, 
  • Abdominal discomfort,
  • Nausea, rash, and edema. 
  • Vitamin B12 deficiency, low magnesium levels, and long-term fundic gland polyps. 

Vonoprazan Tablets Storage

This medication should be stored in a cool dry place and away from the reach of children. Further, In case there are any recommendations about storage, please follow them. 

Vonoprazan Interactions

There are certain medications along with which vonoprazan should not be taken. One such medication is Rilpivirine. It interacts with rilpivirine. Vonoprazan will decrease the level or effect of rilpivirine by inhibiting its absorption into the body. Other medications with which it may have serious interactions are-

  • Alfentanil
  • Carbamazepine
  • Carbonyl iron
  • Cilostazol
  • Citalopram
  • Clonidine
  • Clopidogrel
  • Colchicine
  • Cyclosporine
  • Dihydroergotamine
  • Disopyramide
  • Ergotamine
  • Ethosuximide
  • Everolimus
  • Fentanylamobarbital
  • Apalutamide
  • Armodafinil
  • Atazanavir
  • Belzutifan
  • Bexarotene
  • Bosentan
  • Butabarbital
  • Butalbital
  • Carbamazepine
  • Cenobamate
  • Dabrafenib
  • Dasatinib
  • Efavirenz
  • Elagolix
  • Encorafenib
  • Enzalutamide
  • Erlotinib
  • Eslicarbazepine acetate
  • Etravirine
  • Fosphenytoin
  • Ivosidenib
  • lorlatinib
  • lumacaftor/ivacaftor
  • Mavacamten
  • Mitapivat
  • Mitotane
  • Modafinil
  • Nafcillin
  • Nelfinavir
  • Pentobarbital
  • Pexidartinib
  • Phenobarbital
  • Phenytoin
  • Primidone
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Sotorasib

Frequently Asked Questions 

Ques. What to do if I miss a dose of Vonoprazan?

Ans. In case of erosive esophagitis or heartburn, take it within 12 hr of the missed dose and administer the next dose at a regularly scheduled time. Continue this till the prescribed duration of the medication is completed. 

In case it is a part of treatment for H pylori infection, take it within 4 hr of a missed dose and administer the next dose at a regularly scheduled time. Continue this till the prescribed duration of the medication is completed.

Ques. Is Vonoprazan more effective than other medications for acidity?

Vonoprazan is considered to be more effective in reducing stomach acid because it uses a more effective and efficient mechanism.

Ques. How long does it take for Vonoprazan to start reducing acidity?

Vonoprazan is a fast-acting medication that reduces acid production within hours of taking the medication.

Ques. What are Vonoprazan brand names in India?

Ans. There are too many brands in India.
1. Lupivon: Sold by Lupin Limited, this brand is available in 10 mg and 20 mg strengths
2. Voltapraz: Sold by Sun Pharmaceutical Industries, this brand is available in 10 mg and 20 mg strengths
3. Vozan: Sold by Eris Lifesciences Limited, this brand is used to treat stomach ulcers and GERD
4. Vono: Sold by Dr. Reddy’s Laboratories Limited
5. Kabvie: Sold by Torrent Pharmaceuticals Limited
6. Vonoquench: Sold by La Renon Healthcare Pvt Ltd
7. Vonalong: Sold by Mankind Pharma Ltd
8. Pasivon: Sold by Cipla Ltd
9. Civano: Sold by Cipla Ltd
10. Vonozan: Sold by Deltas Pharma

Ofloxacin and Metronidazole Combination Oral Suspension Use For Babies Precautions, Benefits and Side Effects

Ofloxacin and Metronidazole Combination Oral Suspension Use For Babies: Precautions, Benefits and Side Effects

Ofloxacin and Metronidazole combination oral suspension is widely used to treat bacterial and protozoal infections. The suspension form is often used for the treatment of infections in babies. Protozoans and bacteria are different in cell structure and size, and these infections need different types of treatment.

How Do Ofloxacin and Metronidazole Combination Oral Suspension Work? 

This oral suspension works by combining the benefits of two medications. The first medication that is a part of this combination is Ofloxacin, a type of fluoroquinolone antibiotic (large spectrum antibiotic). Metronidazole is a nitroimidazole type of antibiotic. Nitroimidazole antibiotics are a type of antibiotic that is most commonly used to treat anaerobic bacterial and parasitic infections. This medication in its oral suspension form is often prescribed to babies. 

How Does Ofloxacin Work? 

This medication works by preventing the bacteria from replicating. It does this by stopping the production of bacterial DNA gyrase and topoisomerase IV enzymes. By stopping the production of these two enzymes, this also prevents the bacteria from repairing itself. 

How Does Metronidazole Work? 

This medication works by disrupting the DNA of anaerobic bacteria and protozoa by forming reactive metabolites.

Ofloxacin and Metronidazole Combination Oral Suspension For Babies 

Doctors give this oral suspension medication to babies for the following types of infections.

1. Gastrointestinal Infections or stomach-related infections: This includes both mild diarrhea and a severe form of diarrhea called Dysentery.

2. A patient takes it to treat parasitic infections such as amoebiasis and giardiasis. 

3. Further, a patient can also take it for bacterial infections of the digestive tract as well as other infections caused by bacteria. 

4. A doctor can give this medication to a patient to prevent a wide range of infections that may occur after surgery.

Dosage and Duration 

The recommended dosage is half a teaspoon twice daily for children below ten years. For children above 10 years, the recommended dosage is two to four teaspoons twice a day. The dosage of this medication depends upon the following factors – 

  • Baby’s age 
  • Baby’s weight 
  • The severity of the infection 

Usually, doctors don’t give this medication to children below 1 year. The standard Dosage varies as follows according to age. 

Based on AgeDosage
Between 1-6 years5ml twice daily
Between 7 – 12 years of age10ml twice daily

What if you Miss a Dose?

Give the missed dose as soon as you remember it. In case the missed dose is too close to the next dose, do not take it and consult your doctor.

Always follow the doctor’s instructions concerning dosage and duration. Not completing the prescribed duration of the medication can lead to relapse or resistance.

Ofloxacin and Metronidazole Combination Oral Suspension – Side Effects 

 Some common side effects of this medication include nausea and vomiting. There are a few rare side effects as well. These are allergic reactions, abdominal pain, or dizziness. 

Ofloxacin and Metronidazole Combination Oral Suspension – Precautions

 This medication is not for viral infections such as colds or flu.

 For safe and effective use of this medication, consult a pediatrician before giving this medication to your baby. 

How to Store Ofloxacin and Metronidazole Combination Oral Suspension

Store the medication in a cool dry place away from direct sunlight. A person can use the original packaging for storing the medication. Keep the bottle tightly closed when not in use. The storage instructions would also be there on the packaging. Carefully dispose of the unused medication in such a manner that it is not consumed by animals.

Frequently Asked Questions

Ques. What is this medication used for?

Ans. This medication is used for the treatment of bacterial and protozoan infections.

Ques. Can I stop this medication once my baby feels better?

Ans. No, you have to complete the prescribed course. Not completing the course can lead to a relapse of the infection.

Ques. Are these antibiotics safe for babies?

Ans. Yes, this medication is safe for babies when it is given under the guidance and monitoring of a pediatrician.

Ques. What happens if my baby misses a dose?

Ans. Consult your pediatrician immediately.